Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C1I23_RS01900 Genome accession   NZ_CP025747
Coordinates   393483..394115 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ML35     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 388483..399115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1I23_RS01875 (C1I23_01880) yhfG 388615..388782 (+) 168 WP_000736862.1 YhfG family protein -
  C1I23_RS01880 (C1I23_01885) fic 388772..389374 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C1I23_RS01885 (C1I23_01890) pabA 389406..389969 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C1I23_RS01890 (C1I23_01895) argD 390055..391275 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C1I23_RS01895 (C1I23_01900) yhfK 391342..393432 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C1I23_RS01900 (C1I23_01905) crp 393483..394115 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C1I23_RS01910 (C1I23_01915) yhfA 394417..394821 (+) 405 WP_001148908.1 OsmC family protein -
  C1I23_RS01915 (C1I23_01920) prkB 394876..395745 (-) 870 WP_001274680.1 phosphoribulokinase -
  C1I23_RS01920 (C1I23_01925) yheU 395799..396017 (-) 219 WP_000907085.1 YheU family protein -
  C1I23_RS01925 (C1I23_01930) yheT 396011..397033 (-) 1023 WP_000057356.1 hydrolase -
  C1I23_RS01930 (C1I23_01935) yheS 397033..398946 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=219754 C1I23_RS01900 WP_000242755.1 393483..394115(-) (crp) [Escherichia coli strain ML35]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=219754 C1I23_RS01900 WP_000242755.1 393483..394115(-) (crp) [Escherichia coli strain ML35]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment