Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   LLG50_RS11150 Genome accession   NZ_CP025500
Coordinates   2267026..2268996 (-) Length   656 a.a.
NCBI ID   WP_201261401.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G50     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2262026..2273996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLG50_RS11120 (LLG50_11120) - 2262479..2262679 (+) 201 WP_003131983.1 hypothetical protein -
  LLG50_RS11125 (LLG50_11125) glnA 2262738..2264078 (-) 1341 WP_003131984.1 type I glutamate--ammonia ligase -
  LLG50_RS11130 (LLG50_11130) - 2264140..2264505 (-) 366 WP_003131985.1 MerR family transcriptional regulator -
  LLG50_RS11135 (LLG50_11135) - 2264606..2265043 (-) 438 WP_015427213.1 low molecular weight protein-tyrosine-phosphatase -
  LLG50_RS11140 (LLG50_11140) ruvB 2265192..2266193 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  LLG50_RS11145 (LLG50_11145) ruvA 2266320..2266913 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  LLG50_RS11150 (LLG50_11150) hexB 2267026..2268996 (-) 1971 WP_201261401.1 DNA mismatch repair endonuclease MutL Machinery gene
  LLG50_RS11155 (LLG50_11155) - 2269125..2269820 (-) 696 WP_023190211.1 hypothetical protein -
  LLG50_RS11160 (LLG50_11160) hexA 2269935..2272457 (-) 2523 WP_012898701.1 DNA mismatch repair protein MutS Machinery gene
  LLG50_RS11165 (LLG50_11165) - 2272651..2272998 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73699.99 Da        Isoelectric Point: 5.3227

>NTDB_id=219224 LLG50_RS11150 WP_201261401.1 2267026..2268996(-) (hexB) [Lactococcus lactis subsp. lactis strain G50]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSMP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKETLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQASNDSSEQTFDNFTE
NQLNTDAVSEKMTDRTVESTTEITDKSLENTVSNFGIDFDNEAKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=219224 LLG50_RS11150 WP_201261401.1 2267026..2268996(-) (hexB) [Lactococcus lactis subsp. lactis strain G50]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGTTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATGCCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAGGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
AACTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAG
AATCAACTTAATACAGATGCTGTCAGTGAAAAAATGACTGACAGAACTGTTGAAAGTACTACTGAAATTACTGACAAGAG
CCTAGAAAATACTGTCAGCAACTTTGGAATTGATTTTGATAATGAAGCAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATCAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCGCC
ATATTTGTTCACTTTAGCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAGTCGGCTAGAGCTTTACTCGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(455-598)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.836

99.238

0.564

Multiple sequence alignment