NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	CWI22_RS12570	Genome accession	NZ_CP025053
Coordinates	2594422..2595093 (+)	Length	223 a.a.
NCBI ID	WP_023086109.1	Uniprot ID	-
Organism	Pseudomonas aeruginosa strain PB354
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2589422..2600093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWI22_RS12535 (CWI22_12535)	ppyR	2589895..2590152 (+)	258	WP_023086108.1	psl/pyoverdine operon transcriptional regulator PpyR	-
CWI22_RS12540 (CWI22_12540)	-	2590139..2591332 (+)	1194	WP_003122598.1	NnrS family protein	-
CWI22_RS12545 (CWI22_12545)	-	2591333..2591599 (-)	267	WP_003115326.1	DUF5329 domain-containing protein	-
CWI22_RS12550 (CWI22_12550)	-	2591583..2592476 (-)	894	WP_003115327.1	hypothetical protein	-
CWI22_RS12555 (CWI22_12555)	-	2592503..2593585 (-)	1083	WP_003113385.1	hypothetical protein	-
CWI22_RS12560 (CWI22_12560)	-	2593800..2594108 (+)	309	WP_003090497.1	PepSY domain-containing protein	-
CWI22_RS12565 (CWI22_12565)	-	2594108..2594422 (+)	315	WP_003097704.1	PepSY domain-containing protein	-
CWI22_RS12570 (CWI22_12570)	ciaR	2594422..2595093 (+)	672	WP_023086109.1	two-component system response regulator CarR	Regulator
CWI22_RS12575 (CWI22_12575)	carS	2595090..2596427 (+)	1338	WP_003090493.1	two-component system sensor histidine kinase CarS	-
CWI22_RS12580 (CWI22_12580)	-	2596518..2596826 (+)	309	WP_003113384.1	hypothetical protein	-
CWI22_RS31775	-	2596831..2597367 (-)	537	Protein_2442	methyl-accepting chemotaxis protein	-
CWI22_RS31780	-	2597737..2598975 (-)	1239	Protein_2443	chemotaxis protein	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 24787.23 Da Isoelectric Point: 5.5825

                                >NTDB_id=216985 CWI22_RS12570 WP_023086109.1 2594422..2595093(+) (ciaR) [Pseudomonas aeruginosa strain PB354]

MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA

RDSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR

YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide

Download Length: 672 bp

                                >NTDB_id=216985 CWI22_RS12570 WP_023086109.1 2594422..2595093(+) (ciaR) [Pseudomonas aeruginosa strain PB354]

ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT

GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAACCCTACGACCTGATCATCCTCGACCTCGGCC

TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGGCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG

CGCGATTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA

GCTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC

GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC

TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA

TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG

GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)

Response regulator receiver domain (Response_reg)

(4-112)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	37.727	98.655	0.372
ciaR	Streptococcus pneumoniae Rx1	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae D39	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae TIGR4	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae R6	37.273	98.655	0.368
vicR	Streptococcus mutans UA159	35.965	100	0.368
micA	Streptococcus pneumoniae Cp1015	36.123	100	0.368

Detailed information NTG0216985