Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   CWI26_RS01310 Genome accession   NZ_CP025043
Coordinates   246784..248145 (-) Length   453 a.a.
NCBI ID   WP_100881082.1    Uniprot ID   -
Organism   Streptococcus suis strain AH681     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 241784..253145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS12135 - 242493..242891 (-) 399 WP_024378071.1 hypothetical protein -
  CWI26_RS01280 (CWI26_01280) - 243115..243342 (+) 228 WP_024378070.1 hypothetical protein -
  CWI26_RS01285 (CWI26_01285) - 243323..243628 (+) 306 WP_044672279.1 hypothetical protein -
  CWI26_RS01290 (CWI26_01290) - 243919..244260 (+) 342 WP_024378069.1 LytTR family DNA-binding domain-containing protein -
  CWI26_RS01295 (CWI26_01295) comE/blpR 244260..245000 (+) 741 WP_024376264.1 response regulator transcription factor Regulator
  CWI26_RS01300 (CWI26_01300) - 245010..246341 (+) 1332 WP_100881080.1 GHKL domain-containing protein -
  CWI26_RS01305 (CWI26_01305) - 246538..246687 (-) 150 WP_100881081.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  CWI26_RS01310 (CWI26_01310) comB 246784..248145 (-) 1362 WP_100881082.1 bacteriocin secretion accessory protein Regulator
  CWI26_RS01315 (CWI26_01315) comA/nlmT 248155..250308 (-) 2154 WP_024376267.1 peptide cleavage/export ABC transporter Regulator
  CWI26_RS01320 (CWI26_01320) - 250613..250843 (+) 231 WP_024376268.1 bacteriocin class II family protein -
  CWI26_RS01325 (CWI26_01325) - 250845..251036 (+) 192 WP_024376269.1 hypothetical protein -
  CWI26_RS11925 - 251524..251679 (+) 156 WP_158293388.1 hypothetical protein -
  CWI26_RS11930 - 251699..251839 (+) 141 WP_153308672.1 hypothetical protein -
  CWI26_RS01330 (CWI26_01330) - 251854..252465 (+) 612 WP_024378066.1 CPBP family intramembrane glutamic endopeptidase -
  CWI26_RS01335 (CWI26_01335) - 252627..252923 (+) 297 WP_024376271.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 49558.86 Da        Isoelectric Point: 5.1139

>NTDB_id=216587 CWI26_RS01310 WP_100881082.1 246784..248145(-) (comB) [Streptococcus suis strain AH681]
MNTNLFRSAEFYQRRYHNFATLLILPLVLLVSFLFLFSFLAKKEVTVTSRGEITPTKVIASIQSTSNNPILANHLVANQA
VKKGDALIQYAETMEASQKQALESQVHNLEEQKKGLETLRNSLEQGTNLFTGEDNFGYGATFQQFVSQTQDLELGIAKTN
AEVTNQAALANHTAAAIDQQLSQLQQDIIAYEELKTAISTQASSLPTGNPHQATLNNYLAQVQGTPNPALSDQYISQINQ
TIAGLENSMASLSIQRAGTGSIATYDTSLATKIESLRAQFLQNAAQQLTTVESQLLQAKSQLDQAATQLEQTTITAPENG
VIALNPEFEGKNLIPVGSDIAYLYPDIKQTKTVLITYYVTSEYVALLKEGQTARLSLEKIGNQPIIVIGSIQSIAQSATP
TEEGNLFKITAQATITENESSLLQYGLQGRVTSVIAKKTFFDYCKDKLLHTNH

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=216587 CWI26_RS01310 WP_100881082.1 246784..248145(-) (comB) [Streptococcus suis strain AH681]
ATGAATACAAACCTATTTCGAAGTGCTGAATTTTATCAGCGACGCTACCATAATTTTGCGACCCTTTTGATTCTCCCCTT
GGTACTACTGGTCTCCTTCCTTTTTCTCTTCTCCTTCCTAGCTAAAAAAGAAGTCACTGTCACTTCACGAGGAGAGATTA
CTCCTACCAAGGTCATCGCCTCCATTCAATCAACCAGTAACAATCCTATTCTTGCCAATCATCTCGTAGCCAATCAAGCC
GTAAAAAAAGGCGATGCTCTCATCCAGTACGCCGAAACAATGGAGGCTTCCCAGAAGCAAGCCTTAGAAAGTCAAGTTCA
TAACCTAGAAGAGCAGAAAAAAGGGTTGGAGACCTTACGAAACAGTCTTGAACAGGGTACCAACCTCTTTACAGGAGAAG
ATAACTTTGGCTACGGAGCAACCTTTCAGCAATTCGTCAGCCAAACACAAGACCTAGAATTAGGTATCGCTAAAACGAAT
GCCGAGGTCACTAATCAAGCAGCTTTGGCCAATCACACCGCTGCTGCTATTGACCAACAACTCAGTCAACTCCAGCAGGA
CATCATCGCCTACGAGGAGCTTAAAACAGCGATTAGCACCCAAGCAAGTAGCTTGCCGACAGGCAATCCCCACCAGGCCA
CTCTGAACAACTACCTAGCCCAAGTCCAAGGAACACCAAATCCTGCCCTTAGTGATCAATACATCAGCCAGATTAACCAA
ACCATCGCAGGATTGGAAAACTCAATGGCTAGCCTCTCTATTCAACGGGCAGGTACTGGTAGCATCGCCACCTACGACAC
AAGTCTAGCGACTAAAATCGAAAGTTTACGTGCCCAGTTTCTACAAAACGCAGCTCAGCAACTGACCACTGTCGAATCTC
AATTGCTTCAGGCAAAGTCGCAACTCGATCAAGCAGCTACTCAATTAGAACAAACTACCATTACCGCTCCAGAAAATGGT
GTCATCGCCCTAAATCCTGAGTTCGAGGGAAAAAACTTGATTCCAGTAGGGAGCGATATCGCCTATCTCTATCCTGATAT
CAAGCAAACCAAGACCGTCCTTATCACCTACTATGTGACTTCGGAGTATGTCGCCCTCCTCAAAGAAGGCCAGACCGCCC
GACTAAGCTTAGAGAAAATCGGCAATCAGCCAATCATAGTCATCGGCTCCATCCAGTCTATCGCTCAATCCGCAACACCG
ACAGAAGAGGGCAATCTCTTTAAGATTACAGCCCAAGCTACCATTACAGAAAATGAAAGCTCACTTCTACAGTATGGTCT
ACAGGGTCGCGTCACCAGTGTGATTGCTAAGAAGACCTTCTTCGACTACTGCAAAGACAAACTGCTTCACACAAATCATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

37.778

99.338

0.375
  comB Streptococcus mitis NCTC 12261

37.556

99.338

0.373
  comB Streptococcus pneumoniae D39

37.333

99.338

0.371
  comB Streptococcus pneumoniae R6

37.333

99.338

0.371
  comB Streptococcus pneumoniae Rx1

37.333

99.338

0.371
  comB Streptococcus mitis SK321

36.889

99.338

0.366
  comB Streptococcus gordonii str. Challis substr. CH1

36.807

99.558

0.366