Detailed information NTG0216332

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: BWR56_RS07385
• Genome accession: NZ_CP019562
• Coordinates: 1531030..1531686 (+)
• Length: 218 a.a.
• NCBI ID: WP_076984754.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain S.MIT/ORALIS-351
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1526030..1536686

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWR56_RS07345 (BWR56_1456)	-	1526137..1527618 (-)	1482	WP_076984750.1	M protein trans-acting positive regulator PRD domain-containing protein	-
BWR56_RS07350 (BWR56_1457)	-	1527915..1528151 (+)	237	WP_000964741.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
BWR56_RS07355 (BWR56_1458)	amaP	1528251..1528814 (+)	564	WP_076984751.1	alkaline shock response membrane anchor protein AmaP	-
BWR56_RS07360 (BWR56_1459)	-	1528825..1528995 (+)	171	WP_000454669.1	DUF2273 domain-containing protein	-
BWR56_RS07365 (BWR56_1460)	-	1529007..1529591 (+)	585	WP_000072931.1	Asp23/Gls24 family envelope stress response protein	-
BWR56_RS07370 (BWR56_1461)	-	1529633..1529836 (+)	204	WP_076984752.1	CsbD family protein	-
BWR56_RS07375	-	1529956..1530378 (-)	423	Protein_1440	thiol-disulfide isomerase	-
BWR56_RS07380 (BWR56_1463)	-	1530505..1530960 (-)	456	WP_076984753.1	GNAT family N-acetyltransferase	-
BWR56_RS07385 (BWR56_1464)	cclA/cilC	1531030..1531686 (+)	657	WP_076984754.1	prepilin peptidase	Machinery gene
BWR56_RS07390 (BWR56_1465)	-	1531738..1532454 (+)	717	WP_081390681.1	EcsC family protein	-
BWR56_RS09860	-	1532598..1532714 (+)	117	Protein_1444	prepilin peptidase	-
BWR56_RS07395 (BWR56_1466)	trpA	1532686..1533462 (-)	777	WP_076984756.1	tryptophan synthase subunit alpha	-
BWR56_RS07400 (BWR56_1467)	trpB	1533455..1534678 (-)	1224	WP_076984757.1	tryptophan synthase subunit beta	-
BWR56_RS07405 (BWR56_1468)	-	1534656..1535255 (-)	600	WP_196769359.1	phosphoribosylanthranilate isomerase	-
BWR56_RS07410 (BWR56_1469)	trpC	1535242..1536009 (-)	768	WP_076984759.1	indole-3-glycerol phosphate synthase TrpC	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 24972.22 Da
• Isoelectric Point: 8.0892

>NTDB_id=216332 BWR56_RS07385 WP_076984754.1 1531030..1531686(+) (cclA/cilC) [Streptococcus oralis strain S.MIT/ORALIS-351]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIFPSSHCDSCQTRLRPLDLIPILSQVVNRFRCRYCKIRYPFWYALFELGLG
LLFLAWSWGWISLGQVILITAGLTLGIYDFRHQEYPLLVWLTFHLILMAFCGWSLIMLFFLVLGIIAHFIDIRMGAGDFL
FLASCALVFSATELLILIQFASAAGILAFLSQKKKERLPFVPFLLLATCVIIWCKLIL

Nucleotide

• Length: 657 bp

>NTDB_id=216332 BWR56_RS07385 WP_076984754.1 1531030..1531686(+) (cclA/cilC) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCTTTCTTGGGTTTGGTCATTGACCGTTTTCCAGAGCA
GTCTATTATCTTTCCTTCTAGCCACTGCGATTCCTGTCAAACTCGCTTGCGTCCGCTAGATTTGATTCCTATCCTTTCGC
AGGTGGTTAATCGTTTTCGCTGTCGCTACTGCAAGATTCGCTATCCATTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTAGCTTGGTCTTGGGGGTGGATTTCCTTGGGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGCTGACGTTCCATCTAATCCTCATGGCTTTCTGTGGTTGGA
GTCTGATTATGCTCTTCTTCCTTGTTCTAGGAATCATAGCCCATTTTATCGATATTCGCATGGGCGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCTCTCGTCTTTAGCGCGACCGAATTACTCATCTTGATCCAGTTTGCTTCTGCGGCAGGGATTTT
AGCCTTTCTTTCGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTGGT
GTAAATTAATATTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	89.45	100	0.895
cclA/cilC	Streptococcus mitis SK321	88.073	100	0.881
cclA/cilC	Streptococcus pneumoniae Rx1	85.78	100	0.858
cclA/cilC	Streptococcus pneumoniae D39	85.78	100	0.858
cclA/cilC	Streptococcus pneumoniae R6	85.78	100	0.858
cclA/cilC	Streptococcus pneumoniae TIGR4	85.321	100	0.853