Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BWR56_RS06085 Genome accession   NZ_CP019562
Coordinates   1242252..1242992 (-) Length   246 a.a.
NCBI ID   WP_070567629.1    Uniprot ID   A0A1E9FZB1
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1237252..1247992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS06065 (BWR56_1202) msrB 1238750..1239688 (-) 939 WP_076984655.1 peptide-methionine (R)-S-oxide reductase MsrB -
  BWR56_RS06075 (BWR56_1204) thrB 1239947..1240816 (-) 870 WP_076984656.1 homoserine kinase -
  BWR56_RS06080 (BWR56_1205) - 1240818..1242104 (-) 1287 WP_076984657.1 homoserine dehydrogenase -
  BWR56_RS06085 (BWR56_1206) mecA 1242252..1242992 (-) 741 WP_070567629.1 adaptor protein MecA Regulator
  BWR56_RS06090 (BWR56_1207) - 1243115..1244593 (+) 1479 WP_049490167.1 oligosaccharide flippase family protein -
  BWR56_RS06095 (BWR56_1208) - 1244640..1247168 (-) 2529 WP_076984658.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28524.32 Da        Isoelectric Point: 4.1097

>NTDB_id=216327 BWR56_RS06085 WP_070567629.1 1242252..1242992(-) (mecA) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETENKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=216327 BWR56_RS06085 WP_070567629.1 1242252..1242992(-) (mecA) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACGGAGAATAAGAAAGAACCTTATATCTACTATATCCTACGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9FZB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48

Multiple sequence alignment