Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   BWR56_RS02030 Genome accession   NZ_CP019562
Coordinates   423636..425537 (+) Length   633 a.a.
NCBI ID   WP_076984344.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 418636..430537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS02015 (BWR56_0395) fmt 420642..421577 (+) 936 WP_076984342.1 methionyl-tRNA formyltransferase -
  BWR56_RS02020 (BWR56_0396) rsmB 421570..422883 (+) 1314 WP_196769367.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BWR56_RS02025 (BWR56_0397) - 422899..423639 (+) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BWR56_RS02030 (BWR56_0398) stkP 423636..425537 (+) 1902 WP_076984344.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BWR56_RS02035 (BWR56_0399) - 425625..426383 (+) 759 WP_076984345.1 threonine/serine exporter family protein -
  BWR56_RS02040 (BWR56_0400) - 426385..426840 (+) 456 WP_076984346.1 threonine/serine exporter family protein -
  BWR56_RS02045 (BWR56_0401) - 426959..428131 (+) 1173 WP_081390685.1 hydroxymethylglutaryl-CoA synthase -
  BWR56_RS02050 (BWR56_0402) - 428131..429405 (+) 1275 WP_076984348.1 hydroxymethylglutaryl-CoA reductase, degradative -
  BWR56_RS02055 (BWR56_0403) - 429756..430013 (+) 258 WP_076984349.1 hypothetical protein -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68993.33 Da        Isoelectric Point: 9.2770

>NTDB_id=216309 BWR56_RS02030 WP_076984344.1 423636..425537(+) (stkP) [Streptococcus oralis strain S.MIT/ORALIS-351]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIAIPNVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTI
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVIEVSTASEGTAEGTVVDQTP
KAGEKVDLASTRIKISIYKPKTPPSTSSSNPAQRGNQGSTTTPNQGNQQGNQQGNNPPTNQPNNEGNRESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=216309 BWR56_RS02030 WP_076984344.1 423636..425537(+) (stkP) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGCGAAGCGAGGGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATTAAAGAACACTATCC
TCTTTCAAACGAAGAAGCAGTTCGGATCATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGCATTGTTC
ACCGCGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCTGTAGCC
TTTGCGGAGACTAGTCTGACCCAGACAAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAAATGCTTACGGGACATATCCCTTATGATG
GGGATAGTGCGGTTACGATTGCCCTCCAGCATTTCCAGAAACCACTTCCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATTAAGGCAACTGCTAAGAAGCTGTCAGATCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGTTTGTCTTATAATCGTCGCAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACGA
AGACTTTGCCTAAAGTTCCACAAAGTACACTGACATCTATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCGGTCGCAGAGCCGGCTCCAGCGCCAAAGCCAGCTAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTCTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTGCTATTCCTA
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCTGGTGAAGAAAAGTCAGAA
GCCAGCGATACCGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGATGTTGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCAGGAACTATC
CTCAGACAAACCCCCGCTTCGGGTTCGACTTATGACCTTTCAAAAGCCACCACGATTACCTTAACAGTTGCCAAGAAGGT
GACCAGTGTCAGCATGCCTAGCTACATCGGCTCAAGTCTCGAATTTACTAAGAATAATCTGACTCAGATTGTCGGAGTAA
AAGAGGCTAATATTGAGGTTATTGAAGTATCGACTGCTTCTGAAGGAACAGCAGAGGGTACGGTTGTAGATCAAACACCA
AAAGCTGGTGAAAAGGTTGATCTTGCTAGCACACGTATCAAGATTTCGATTTACAAACCGAAAACACCACCGTCAACTTC
ATCCTCTAACCCTGCTCAACGAGGGAACCAGGGTTCTACAACAACACCAAATCAAGGGAACCAGCAAGGAAATCAACAAG
GGAATAATCCTCCAACGAATCAACCAAACAATGAAGGAAACCGCGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.328

92.575

0.725
  stkP Streptococcus pneumoniae D39

77.986

92.575

0.722
  stkP Streptococcus pneumoniae R6

77.986

92.575

0.722
  stkP Streptococcus pneumoniae Rx1

77.816

92.575

0.72
  pknB Streptococcus mutans UA159

56.153

91.153

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

53.859

92.101

0.496

Multiple sequence alignment