Detailed information NTG0216221

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: BZG42_RS04255
• Genome accession: NZ_CP019557
• Coordinates: 883767..884441 (+)
• Length: 224 a.a.
• NCBI ID: WP_120171596.1
• Uniprot ID: -
• Organism: Streptococcus sp. DAT741
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 878767..889441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZG42_RS04230 (BZG42_04265)	pstC	879340..880257 (+)	918	WP_120171594.1	phosphate ABC transporter permease subunit PstC	-
BZG42_RS04235 (BZG42_04270)	pstA	880247..881134 (+)	888	WP_024531693.1	phosphate ABC transporter permease PstA	-
BZG42_RS04240 (BZG42_04275)	pstB	881160..881963 (+)	804	WP_024531694.1	phosphate ABC transporter ATP-binding protein PstB	-
BZG42_RS04245 (BZG42_04280)	pstB	881975..882733 (+)	759	WP_155996307.1	phosphate ABC transporter ATP-binding protein PstB	-
BZG42_RS04250 (BZG42_04285)	phoU	882763..883419 (+)	657	WP_024531696.1	phosphate signaling complex protein PhoU	-
BZG42_RS04255 (BZG42_04290)	ciaR	883767..884441 (+)	675	WP_120171596.1	response regulator transcription factor	Regulator
BZG42_RS04260 (BZG42_04295)	ciaH	884434..885804 (+)	1371	WP_155963845.1	HAMP domain-containing sensor histidine kinase	Regulator
BZG42_RS04265 (BZG42_04300)	-	885977..886741 (+)	765	WP_227990319.1	hypothetical protein	-
BZG42_RS04270 (BZG42_04305)	-	886741..887532 (+)	792	WP_227990321.1	hypothetical protein	-
BZG42_RS10080	-	887439..887924 (+)	486	WP_227990323.1	DUF1266 domain-containing protein	-
BZG42_RS04275 (BZG42_04310)	rpsT	888212..888460 (-)	249	WP_075098301.1	30S ribosomal protein S20	-
BZG42_RS04280 (BZG42_04315)	coaA	888519..889439 (-)	921	WP_024531701.1	type I pantothenate kinase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25416.23 Da
• Isoelectric Point: 4.2606

>NTDB_id=216221 BZG42_RS04255 WP_120171596.1 883767..884441(+) (ciaR) [Streptococcus sp. DAT741]
MIKILLIEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAEMGIYDLILLDLMLPEKDGFQVLKELREKGVVTPVLITTA
KESLEDKGHGFELGADDYLIKPFYLEELKMRIQALLKRAGKFNEESTLSFGDILVDLSTNTTTVNGQPVELLGKEFDLLV
YFLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGEHLQTLRSVGYILKND

Nucleotide

• Length: 675 bp

>NTDB_id=216221 BZG42_RS04255 WP_120171596.1 883767..884441(+) (ciaR) [Streptococcus sp. DAT741]
ATGATTAAAATCTTATTGATAGAAGATGATTTGAGTCTATCCAATTCAGTCTTTGATTTTTTGGATGACTTTGCAGATGT
CATGCAAGTCTTTGATGGCGAAGAAGGAATCTATGAAGCAGAGATGGGGATTTACGATTTGATTCTCTTAGACTTGATGT
TGCCTGAAAAGGATGGTTTCCAAGTATTGAAAGAGTTACGTGAGAAGGGTGTGGTAACGCCAGTTCTCATCACTACAGCT
AAAGAAAGCTTGGAAGATAAAGGTCATGGTTTTGAATTGGGAGCAGATGATTACCTCATTAAGCCATTTTACTTAGAGGA
GCTGAAAATGCGCATTCAAGCCCTATTAAAACGGGCTGGTAAATTTAATGAGGAAAGCACACTGAGTTTTGGAGATATCT
TAGTTGATTTGTCCACGAATACGACAACCGTGAATGGTCAACCAGTTGAATTGCTGGGGAAAGAATTTGATTTGTTAGTC
TACTTCCTACAGAATCAGAATGTTATTCTGCCTAAAACACAAATTTTTGATCGCATTTGGGGATTTGACAGTGACACTAC
CATTTCAGTCGTTGAAGTCTACGTATCTAAGGTTCGGAAAAAATTGAAAGGGACGGCTTTTGGGGAACATCTTCAAACCC
TTCGTAGTGTCGGTTATATTTTGAAGAATGACTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-221)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	86.547	99.554	0.862
ciaR	Streptococcus pneumoniae D39	86.547	99.554	0.862
ciaR	Streptococcus pneumoniae R6	86.547	99.554	0.862
ciaR	Streptococcus pneumoniae TIGR4	86.547	99.554	0.862
ciaR	Streptococcus mutans UA159	84.753	99.554	0.844
vicR	Streptococcus mutans UA159	34.322	100	0.362