Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BZG42_RS04260 Genome accession   NZ_CP019557
Coordinates   884434..885804 (+) Length   456 a.a.
NCBI ID   WP_155963845.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 879434..890804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS04235 (BZG42_04270) pstA 880247..881134 (+) 888 WP_024531693.1 phosphate ABC transporter permease PstA -
  BZG42_RS04240 (BZG42_04275) pstB 881160..881963 (+) 804 WP_024531694.1 phosphate ABC transporter ATP-binding protein PstB -
  BZG42_RS04245 (BZG42_04280) pstB 881975..882733 (+) 759 WP_155996307.1 phosphate ABC transporter ATP-binding protein PstB -
  BZG42_RS04250 (BZG42_04285) phoU 882763..883419 (+) 657 WP_024531696.1 phosphate signaling complex protein PhoU -
  BZG42_RS04255 (BZG42_04290) ciaR 883767..884441 (+) 675 WP_120171596.1 response regulator transcription factor Regulator
  BZG42_RS04260 (BZG42_04295) ciaH 884434..885804 (+) 1371 WP_155963845.1 HAMP domain-containing sensor histidine kinase Regulator
  BZG42_RS04265 (BZG42_04300) - 885977..886741 (+) 765 WP_227990319.1 hypothetical protein -
  BZG42_RS04270 (BZG42_04305) - 886741..887532 (+) 792 WP_227990321.1 hypothetical protein -
  BZG42_RS10080 - 887439..887924 (+) 486 WP_227990323.1 DUF1266 domain-containing protein -
  BZG42_RS04275 (BZG42_04310) rpsT 888212..888460 (-) 249 WP_075098301.1 30S ribosomal protein S20 -
  BZG42_RS04280 (BZG42_04315) coaA 888519..889439 (-) 921 WP_024531701.1 type I pantothenate kinase -
  BZG42_RS04285 (BZG42_04320) - 889552..890142 (+) 591 WP_120171599.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51983.78 Da        Isoelectric Point: 7.3167

>NTDB_id=216222 BZG42_RS04260 WP_155963845.1 884434..885804(+) (ciaH) [Streptococcus sp. DAT741]
MTKRFRKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYENSDDTLHRIKEEPAMAVGLAVARAYQPNSELTLQD
NSNRNTTASILDDTMTPQSGNGEQLRLGVNTHVLLYNKNGEIINPDKFTGLSRLTLDKENLDEIRETTVKSSFGLNENYR
YVTIKLVVEELGRYAVYDIKYATILVNVSQIKSSIEKYEATVAVVMVSAWLISILASIYLSNLSMRPILTSYQKQKDFVE
NASHELRTPLAVLQNRLEGLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGFKLDMVEVPPTYFDEIFDN
YIIIAEENGKKVTINNLISQSIRTDKVLIKQLLTILFDNAMKYTDDDCDIQITASIKDKLVCFTIADNGLGITDNDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAQQIIKALNGEIFVRDNQPKGTVFEVQLPIKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=216222 BZG42_RS04260 WP_155963845.1 884434..885804(+) (ciaH) [Streptococcus sp. DAT741]
ATGACTAAGCGATTTAGAAAGCTAGTTTACACGGATAAATTTTCTTTCTTTATCCGCTATTTTGCAGTCTTTACTCTGAT
TTTTGGTCTGATGACAGCTATCATCTTTCAATTGATGCGTTCAACCATGTATGAAAATTCGGATGACACGCTACATCGAA
TCAAAGAAGAACCTGCAATGGCAGTTGGACTGGCAGTGGCGAGAGCCTATCAACCGAATTCAGAACTCACTCTCCAAGAC
AATTCAAATAGGAATACGACGGCTTCCATTTTGGATGATACGATGACGCCCCAAAGCGGAAATGGGGAACAATTGAGGTT
GGGAGTGAATACTCACGTACTGCTGTATAACAAGAATGGTGAAATCATTAACCCTGATAAATTCACCGGCTTATCAAGGT
TGACCTTAGACAAGGAAAATTTAGATGAAATTAGGGAAACGACCGTTAAATCTTCTTTTGGTTTGAATGAAAATTATCGT
TATGTAACGATTAAACTGGTAGTCGAGGAACTCGGTCGTTATGCGGTTTACGATATAAAGTATGCAACTATCCTAGTGAA
TGTTAGCCAAATTAAATCATCTATTGAGAAGTATGAAGCAACAGTTGCTGTTGTAATGGTTTCTGCTTGGTTGATTTCTA
TCTTGGCAAGTATTTACTTGTCCAATCTTAGTATGCGTCCTATTTTGACTAGCTATCAGAAACAAAAGGATTTTGTGGAA
AATGCCAGTCATGAGCTACGTACACCATTAGCTGTTTTACAGAACCGCTTGGAAGGGTTGTTCCGTCATCCTGAAACGAC
CATTTTGGAAAGTAGCGAAAGTATCGGATCTAGTTTGGAGGAGGTCCGCAATATGCGGTTACTGACGACCAATTTGCTCA
ATCTCGCACGCCGGGATGATGGTTTTAAACTAGATATGGTAGAAGTACCTCCTACCTATTTTGATGAAATATTTGATAAC
TATATTATAATTGCTGAAGAAAACGGCAAGAAGGTGACTATCAACAATTTAATTAGCCAGTCTATTCGAACGGACAAAGT
TTTAATTAAGCAATTGCTGACTATCTTATTTGATAATGCAATGAAATACACCGATGATGATTGCGATATTCAAATTACAG
CCAGTATAAAAGATAAATTAGTCTGCTTTACCATTGCGGATAATGGCTTAGGAATTACCGACAACGACAAAAAGAAAATA
TTTGATCGTTTCTATCGGGTTGATAAGGCTAGAACACGTCAAAAGGGTGGATTCGGTCTAGGCTTATCTTTGGCGCAGCA
GATTATCAAGGCTCTGAATGGAGAAATTTTCGTTAGGGATAATCAGCCTAAAGGGACTGTTTTTGAGGTGCAACTTCCAA
TCAAAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(235-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(345-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.781

100

0.498
  ciaH Streptococcus pneumoniae D39

49.781

100

0.498
  ciaH Streptococcus pneumoniae R6

49.781

100

0.498
  ciaH Streptococcus pneumoniae TIGR4

49.781

100

0.498
  ciaH Streptococcus mutans UA159

48.786

99.342

0.485

Multiple sequence alignment