Detailed information NTG0021621

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMA_RS00820
• Genome accession: NC_003116
• Coordinates: 142207..143394 (-)
• Length: 395 a.a.
• NCBI ID: WP_002246734.1
• Uniprot ID: A0A0U1RGV7
• Organism: Neisseria meningitidis Z2491
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 137207..148394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMA_RS00795 (NMA0153)	-	137504..137884 (-)	381	WP_002239423.1	helix-turn-helix domain-containing protein	-
NMA_RS00800 (NMA0154)	-	138003..138554 (+)	552	WP_002230190.1	hypothetical protein	-
NMA_RS00805 (NMA0155)	-	138574..139269 (+)	696	WP_002233407.1	hypothetical protein	-
NMA_RS00810 (NMA0156)	topA	139342..141648 (-)	2307	WP_010981052.1	type I DNA topoisomerase	-
NMA_RS00815 (NMA0157)	-	141720..142181 (-)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMA_RS00820 (NMA0158)	dprA	142207..143394 (-)	1188	WP_002246734.1	DNA-processing protein DprA	Machinery gene
NMA_RS00825 (NMA0159)	-	143485..144762 (-)	1278	WP_002246735.1	sigma-54-dependent transcriptional regulator	-
NMA_RS00830 (NMA0160)	-	144755..146875 (-)	2121	WP_002245785.1	sensor histidine kinase	-
NMA_RS00835 (NMA0161)	-	146875..147474 (-)	600	WP_002216221.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 42072.25 Da
• Isoelectric Point: 6.1732

>NTDB_id=21621 NMA_RS00820 WP_002246734.1 142207..143394(-) (dprA) [Neisseria meningitidis Z2491]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEAAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPSGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=21621 NMA_RS00820 WP_002246734.1 142207..143394(-) (dprA) [Neisseria meningitidis Z2491]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTCTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCCCTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCAAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGACGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGCGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCAGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

• DprA winged helix domain (DprA_WH) (339-387)

3D structure

• AlphaFold DB: A0A0U1RGV7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.203	100	0.962
dprA	Neisseria gonorrhoeae strain FA1090	95.949	100	0.959
dprA	Neisseria meningitidis strain C311	91.688	100	0.922
dprA	Neisseria meningitidis MC58	91.688	100	0.922
dprA	Vibrio cholerae strain A1552	37.531	100	0.377