Detailed information NTG0215770

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: CVO91_RS00225
• Genome accession: NZ_CP024974
• Coordinates: 31396..32130 (+)
• Length: 244 a.a.
• NCBI ID: WP_004195385.1
• Uniprot ID: -
• Organism: Streptococcus suis strain CZ130302
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 26396..37130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVO91_RS00200 (CVO91_00200)	-	26589..27821 (+)	1233	WP_004195374.1	CHAP domain-containing protein	-
CVO91_RS00205 (CVO91_00205)	-	27952..28920 (+)	969	WP_004195376.1	ribose-phosphate diphosphokinase	-
CVO91_RS00210 (CVO91_00210)	-	29007..30185 (+)	1179	WP_004195378.1	pyridoxal phosphate-dependent aminotransferase	-
CVO91_RS00215 (CVO91_00215)	recO	30172..30936 (+)	765	WP_100664705.1	DNA repair protein RecO	Machinery gene
CVO91_RS00220 (CVO91_00220)	-	30948..31289 (-)	342	WP_004195383.1	hypothetical protein	-
CVO91_RS00225 (CVO91_00225)	comE/blpR	31396..32130 (+)	735	WP_004195385.1	response regulator transcription factor	Regulator
CVO91_RS00230 (CVO91_00230)	-	32127..33491 (+)	1365	WP_004195387.1	GHKL domain-containing protein	-
CVO91_RS00235 (CVO91_00235)	-	33814..34551 (+)	738	WP_004195389.1	hypothetical protein	-
CVO91_RS00240 (CVO91_00240)	-	34579..35454 (+)	876	WP_004195391.1	ABC transporter ATP-binding protein	-
CVO91_RS00245 (CVO91_00245)	-	35456..36229 (+)	774	WP_004195393.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28078.08 Da
• Isoelectric Point: 5.2193

>NTDB_id=215770 CVO91_RS00225 WP_004195385.1 31396..32130(+) (comE/blpR) [Streptococcus suis strain CZ130302]
MLRIFILEDDFMQQARLEQAIEEVVKTSDVAYKTLEVFGKPQQLLEAVTETGNHQLFFLDIEIRGEEKKGMEIAREIRAR
DPHAVIVFVTTHSEFMPLTYKYRVSALDFIDKGLDEPAFKEAVADVLQHAYSHISQTVSDDAFVFKSEFSQIQVPFSDIL
YFETSSTPHKVVLTTKLGHTEFYGKVSDIAKTDERLYQSHRAYVVNPANILRVDAVERMVYFEQEESCLVSRMKLKGLLE
RVGK

Nucleotide

• Length: 735 bp

>NTDB_id=215770 CVO91_RS00225 WP_004195385.1 31396..32130(+) (comE/blpR) [Streptococcus suis strain CZ130302]
ATGTTACGGATTTTTATCTTGGAAGATGATTTTATGCAACAAGCTAGGTTGGAGCAGGCGATTGAGGAAGTTGTAAAAAC
GAGTGACGTTGCCTATAAGACCTTAGAAGTTTTTGGTAAACCTCAGCAGTTATTAGAGGCTGTGACAGAGACTGGAAATC
ATCAGCTCTTTTTCCTAGATATTGAGATTAGAGGTGAGGAGAAGAAAGGGATGGAGATTGCACGGGAGATAAGAGCGCGT
GATCCGCATGCTGTGATTGTTTTTGTGACGACACATTCGGAGTTTATGCCTTTGACCTATAAATACCGTGTGTCGGCTCT
TGATTTTATTGATAAGGGGTTGGATGAGCCTGCCTTTAAGGAAGCAGTGGCAGATGTTCTCCAACATGCTTATAGTCATA
TCAGTCAGACTGTGAGCGATGATGCTTTTGTTTTCAAGAGTGAGTTTTCTCAGATTCAGGTGCCGTTTTCAGATATTTTG
TATTTTGAAACCTCTTCAACGCCTCATAAGGTCGTCTTGACAACCAAGTTAGGTCATACAGAGTTTTATGGCAAGGTGTC
GGATATTGCTAAAACGGATGAACGATTGTACCAGAGCCATCGGGCTTATGTGGTCAATCCTGCTAATATTCTTCGTGTGG
ATGCTGTGGAGCGGATGGTGTATTTTGAACAGGAGGAATCTTGCTTGGTCTCTCGAATGAAACTGAAAGGTTTGCTAGAG
AGGGTTGGGAAATGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-241)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.23	97.951	0.541
comE/comE1	Streptococcus equinus JB1	45.607	97.951	0.447
comE/comE2	Streptococcus equinus JB1	40.336	97.541	0.393
comE	Streptococcus infantis strain Atu-4	36.905	100	0.381
comE/comE2	Streptococcus gordonii strain NCTC7865	37.86	99.59	0.377
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.86	99.59	0.377
comE	Streptococcus mitis NCTC 12261	37.449	99.59	0.373
comE	Streptococcus mitis SK321	37.449	99.59	0.373
comE	Streptococcus pneumoniae Rx1	37.449	99.59	0.373
comE	Streptococcus pneumoniae D39	37.449	99.59	0.373
comE	Streptococcus pneumoniae R6	37.449	99.59	0.373
comE	Streptococcus pneumoniae TIGR4	37.449	99.59	0.373