Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BTR42_RS02140 Genome accession   NZ_CP018822
Coordinates   378667..379422 (+) Length   251 a.a.
NCBI ID   WP_009853397.1    Uniprot ID   A0A060RH68
Organism   Streptococcus gallolyticus subsp. gallolyticus DSM 16831     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 373667..384422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTR42_RS02125 (BTR42_01845) - 374076..375647 (-) 1572 WP_009853395.1 ABC transporter permease subunit -
  BTR42_RS02130 (BTR42_01850) - 375780..377675 (+) 1896 WP_077496195.1 DUF2207 domain-containing protein -
  BTR42_RS02135 (BTR42_01855) - 377727..378566 (+) 840 WP_003063292.1 undecaprenyl-diphosphate phosphatase -
  BTR42_RS02140 (BTR42_01860) mecA 378667..379422 (+) 756 WP_009853397.1 adaptor protein MecA Regulator
  BTR42_RS02145 (BTR42_01865) - 379424..380587 (+) 1164 WP_077496197.1 glycosyltransferase family 4 protein -
  BTR42_RS02150 (BTR42_01870) sufC 380701..381471 (+) 771 WP_003063299.1 Fe-S cluster assembly ATPase SufC -
  BTR42_RS02155 (BTR42_01875) sufD 381545..382807 (+) 1263 WP_077496199.1 Fe-S cluster assembly protein SufD -
  BTR42_RS02160 (BTR42_01880) - 382809..384041 (+) 1233 WP_077496201.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28762.55 Da        Isoelectric Point: 4.0664

>NTDB_id=210614 BTR42_RS02140 WP_009853397.1 378667..379422(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEEVLTEQAQAEPTEEDINPSDYVHYV
LDFPTLEAVVAFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVAKLKMIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=210614 BTR42_RS02140 WP_009853397.1 378667..379422(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAGTAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTGACACCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAGATC
AATAAAGAAATTAATTTTGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGCTTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAGGAAGTTCTCACAGAACAAGCTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTAGCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGCGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTGCAAAATTAAAAATGATTGAGTTGGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RH68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.742

98.805

0.669
  mecA Streptococcus thermophilus LMD-9

60.729

98.406

0.598
  mecA Streptococcus thermophilus LMG 18311

60.324

98.406

0.594
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49

Multiple sequence alignment