Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   CR542_RS00355 Genome accession   NZ_CP024126
Coordinates   59571..60488 (+) Length   305 a.a.
NCBI ID   WP_002935296.1    Uniprot ID   -
Organism   Streptococcus suis strain HA0609     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 54571..65488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR542_RS00335 (CR542_00335) - 54655..56367 (+) 1713 WP_002935303.1 ABC transporter ATP-binding protein -
  CR542_RS11615 - 56469..56642 (+) 174 WP_002935301.1 hypothetical protein -
  CR542_RS00340 (CR542_00340) ruvB 56937..57938 (+) 1002 WP_002935300.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  CR542_RS00345 (CR542_00345) - 57938..58684 (+) 747 WP_002935299.1 GNAT family N-acetyltransferase -
  CR542_RS00350 (CR542_00350) - 58686..59324 (+) 639 WP_002935298.1 HAD-IA family hydrolase -
  CR542_RS00355 (CR542_00355) comR 59571..60488 (+) 918 WP_002935296.1 helix-turn-helix domain-containing protein Regulator
  CR542_RS00360 (CR542_00360) - 60753..61994 (+) 1242 WP_013730059.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  CR542_RS00370 (CR542_00370) - 62163..63686 (+) 1524 WP_004194221.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 36252.32 Da        Isoelectric Point: 4.6744

>NTDB_id=210608 CR542_RS00355 WP_002935296.1 59571..60488(+) (comR) [Streptococcus suis strain HA0609]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide


Download         Length: 918 bp        

>NTDB_id=210608 CR542_RS00355 WP_002935296.1 59571..60488(+) (comR) [Streptococcus suis strain HA0609]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis D9

100

100

1
  comR Streptococcus suis P1/7

62.126

98.689

0.613
  comR Streptococcus suis 05ZYH33

62.126

98.689

0.613
  comR Streptococcus mutans UA159

37

98.361

0.364

Multiple sequence alignment