Detailed information NTG0206937

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: BSR20_RS08585
• Genome accession: NZ_CP018189
• Coordinates: 1866018..1868171 (+)
• Length: 717 a.a.
• NCBI ID: WP_156209940.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC3
• Function: transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1862785..1869620	1866018..1868171	within	0

Gene organization within MGE regions

Location: 1862785..1869620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR20_RS08575 (BSR20_08660)	-	1862785..1863987 (-)	1203	WP_284675887.1	IS110 family transposase	-
BSR20_RS08585 (BSR20_08675)	comA/nlmT	1866018..1868171 (+)	2154	WP_156209940.1	peptide cleavage/export ABC transporter	Regulator
BSR20_RS10495 (BSR20_08680)	-	1868187..1868438 (+)	252	Protein_1645	bacteriocin ABC transporter ATP-binding protein	-
BSR20_RS08595	-	1868491..1869620 (-)	1130	Protein_1646	IS3 family transposase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80441.20 Da
• Isoelectric Point: 6.8880

>NTDB_id=206937 BSR20_RS08585 WP_156209940.1 1866018..1868171(+) (comA/nlmT) [Streptococcus salivarius strain ICDC3]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGLETRAIKADMSLFEMEDV
TYPFIAHVNKDGKLQHYYVIYKSTKDHLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIATIVLASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMITFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVTSRFSDANTIIDAMASTILSLFLDFSIVIIVGGVLLIQNSNLFWLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVSSAIIEDINGIETIKSLTSEEVRYQKIDGEFVDYLDNSLRLSKLSILQTSLKQGAQL
ILNVLILWTGAQMVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSATVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQAGILNACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDQGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=206937 BSR20_RS08585 WP_156209940.1 1866018..1868171(+) (comA/nlmT) [Streptococcus salivarius strain ICDC3]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCGCATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTAGAAACGAGAGCTATAAAGGCTGATATGTCGCTCTTTGAGATGGAAGATGTT
ACTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATCA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTG
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTACTATTGTCTTGGCCAGTCTCTTGGTTACCTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTGGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATAACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCTTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTACCTC
ACGTTTTAGTGATGCTAATACTATTATCGATGCTATGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTACTGATACAAAATAGCAATCTCTTCTGGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTTTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAGTTCAGCTAT
CATTGAGGACATTAATGGGATTGAAACCATAAAATCACTAACCAGCGAAGAAGTACGCTATCAAAAGATTGATGGTGAGT
TTGTTGACTATCTAGACAATTCTCTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGATGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCCTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTACGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGACATCACTGTTACGGATTTGTCCTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTCTGACGAT
TAGACAAGGAGAAAAGATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTAGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCCGGTATTTTGAATGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTTACGAAATCTCCT
GTACTAATCCTAGATGAAGCAACTAGTGGATTGGATGTTTTGACAGAAAAGAAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACAATCATATTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCAGGGAC
GCGTAGTGGAGACAGGCTCTCATCAAGACCTGATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	68.347	99.582	0.681
comA	Streptococcus mitis NCTC 12261	66.245	99.163	0.657
comA	Streptococcus pneumoniae Rx1	65.823	99.163	0.653
comA	Streptococcus pneumoniae D39	65.823	99.163	0.653
comA	Streptococcus pneumoniae R6	65.823	99.163	0.653
comA	Streptococcus mitis SK321	65.541	99.163	0.65
comA	Streptococcus pneumoniae TIGR4	65.401	99.163	0.649
comA	Streptococcus gordonii str. Challis substr. CH1	64.146	99.582	0.639