Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   BSR20_RS05325 Genome accession   NZ_CP018189
Coordinates   1196647..1197354 (-) Length   235 a.a.
NCBI ID   WP_049554316.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1191064..1203806 1196647..1197354 within 0


Gene organization within MGE regions


Location: 1191064..1203806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR20_RS05285 (BSR20_05340) - 1191064..1191741 (+) 678 WP_045771627.1 helix-turn-helix domain-containing protein -
  BSR20_RS10345 (BSR20_05345) - 1191738..1192703 (+) 966 WP_045771628.1 IS3 family transposase -
  BSR20_RS05300 (BSR20_05350) tnpA 1192976..1193392 (-) 417 WP_002886752.1 IS200/IS605 family transposase -
  BSR20_RS05305 (BSR20_05355) - 1193630..1193906 (-) 277 Protein_993 ISL3 family transposase -
  BSR20_RS05310 (BSR20_05360) - 1194078..1194437 (-) 360 WP_156209757.1 YbaN family protein -
  BSR20_RS05315 (BSR20_05365) vicX 1194496..1195308 (-) 813 WP_002885031.1 MBL fold metallo-hydrolase Regulator
  BSR20_RS05320 (BSR20_05370) vicK 1195314..1196654 (-) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BSR20_RS05325 (BSR20_05375) vicR 1196647..1197354 (-) 708 WP_049554316.1 response regulator YycF Regulator
  BSR20_RS05330 (BSR20_05380) - 1197640..1198407 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  BSR20_RS05335 (BSR20_05385) - 1198417..1199250 (+) 834 WP_156209759.1 transporter substrate-binding domain-containing protein -
  BSR20_RS05340 (BSR20_05390) - 1199268..1199966 (+) 699 WP_014633207.1 amino acid ABC transporter permease -
  BSR20_RS05345 (BSR20_05395) - 1199978..1200628 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  BSR20_RS05350 (BSR20_05400) - 1200816..1201583 (+) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  BSR20_RS05355 (BSR20_05405) - 1201595..1202428 (+) 834 WP_111686600.1 transporter substrate-binding domain-containing protein -
  BSR20_RS05360 (BSR20_05410) - 1202446..1203144 (+) 699 WP_014633207.1 amino acid ABC transporter permease -
  BSR20_RS05365 (BSR20_05415) - 1203156..1203806 (+) 651 WP_002886253.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27073.95 Da        Isoelectric Point: 4.8387

>NTDB_id=206922 BSR20_RS05325 WP_049554316.1 1196647..1197354(-) (vicR) [Streptococcus salivarius strain ICDC3]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEVEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=206922 BSR20_RS05325 WP_049554316.1 1196647..1197354(-) (vicR) [Streptococcus salivarius strain ICDC3]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
GGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTAGAGCAGTTTGAAGTTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment