Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   BSR19_RS07485 Genome accession   NZ_CP018187
Coordinates   1665885..1667759 (-) Length   624 a.a.
NCBI ID   WP_156246934.1    Uniprot ID   A0AB37DCJ1
Organism   Streptococcus salivarius strain ICDC2     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1660885..1672759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS07450 (BSR19_07565) rimM 1661265..1661783 (-) 519 WP_156246932.1 ribosome maturation factor RimM -
  BSR19_RS07465 (BSR19_07580) - 1662478..1663122 (-) 645 WP_002891417.1 response regulator transcription factor -
  BSR19_RS07470 (BSR19_07585) - 1663112..1664122 (-) 1011 WP_002891418.1 sensor histidine kinase -
  BSR19_RS07475 (BSR19_07590) liaF 1664119..1664816 (-) 698 Protein_1433 cell wall-active antibiotics response protein LiaF -
  BSR19_RS07480 (BSR19_07595) - 1664980..1665738 (-) 759 WP_156246933.1 potassium channel family protein -
  BSR19_RS07485 (BSR19_07600) stkP/pknB 1665885..1667759 (-) 1875 WP_156246934.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BSR19_RS07490 (BSR19_07605) - 1667759..1668496 (-) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BSR19_RS07495 (BSR19_07610) rsmB 1668540..1669862 (-) 1323 WP_156246935.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BSR19_RS07500 (BSR19_07615) fmt 1669852..1670787 (-) 936 WP_002884812.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67941.66 Da        Isoelectric Point: 6.7045

>NTDB_id=206857 BSR19_RS07485 WP_156246934.1 1665885..1667759(-) (stkP/pknB) [Streptococcus salivarius strain ICDC2]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKNISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=206857 BSR19_RS07485 WP_156246934.1 1665885..1667759(-) (stkP/pknB) [Streptococcus salivarius strain ICDC2]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAACCACTACCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCTTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTACAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCGAAGGTTGATCCAGTTCCATCAGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTCTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTGGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTTCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGACTCTGTCGATACGGGTAAGGTCATCAAGACCGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCAT
TGATGTTTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGTGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCCTTCAATCCTAAGGATAGTAAGGCTAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCAGTTCAAACCTTGAATCGTAAGAATATCT
CAAGTAGTAGCATCGAGTACCACGACTATAATACTGGTGCCAAATTAGATAAGGATAAGGTTCCTAGCAGTACGGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAG
TCTCCAGTCAAGCTCAAGCAGTACGACACATTCGTCATCAACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAATAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

99.038

100

0.99
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae D39

52.151

93.109

0.486
  stkP Streptococcus pneumoniae R6

52.151

93.109

0.486
  stkP Streptococcus pneumoniae Rx1

51.979

93.109

0.484
  stkP Streptococcus pneumoniae TIGR4

52.265

91.987

0.481

Multiple sequence alignment