Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BSR19_RS02785 Genome accession   NZ_CP018187
Coordinates   545816..546559 (-) Length   247 a.a.
NCBI ID   WP_156246501.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC2     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 540816..551559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS02760 (BSR19_02765) rplJ 541949..542452 (+) 504 WP_003095623.1 50S ribosomal protein L10 -
  BSR19_RS02765 (BSR19_02770) rplL 542527..542895 (+) 369 WP_004183006.1 50S ribosomal protein L7/L12 -
  BSR19_RS02770 - 543090..543290 (-) 201 WP_156246495.1 hypothetical protein -
  BSR19_RS02775 (BSR19_02785) - 543693..544259 (+) 567 WP_156246497.1 transcriptional regulator -
  BSR19_RS02780 (BSR19_02790) - 544499..545806 (-) 1308 WP_156246499.1 sensor histidine kinase -
  BSR19_RS02785 (BSR19_02795) comE/blpR 545816..546559 (-) 744 WP_156246501.1 response regulator transcription factor Regulator
  BSR19_RS02790 (BSR19_02805) tnpA 547578..548051 (+) 474 WP_002891962.1 IS200/IS605 family transposase -
  BSR19_RS11795 - 548212..548334 (+) 123 WP_002269975.1 hypothetical protein -
  BSR19_RS11445 (BSR19_02810) - 548391..549467 (+) 1077 WP_414820571.1 CHAP domain-containing protein -
  BSR19_RS02805 (BSR19_02815) - 549525..550118 (+) 594 Protein_503 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28707.20 Da        Isoelectric Point: 6.6125

>NTDB_id=206840 BSR19_RS02785 WP_156246501.1 545816..546559(-) (comE/blpR) [Streptococcus salivarius strain ICDC2]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEKFYERVHLAIEYTMDKMGATIAQDSFTFETATAHVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLFRCHRSFIVNPENIVKINKEEKMVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=206840 BSR19_RS02785 WP_156246501.1 545816..546559(-) (comE/blpR) [Streptococcus salivarius strain ICDC2]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACTGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGTTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCAAAAGAAATTCGGAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATTGATAAAGCTTTGGATGATGAAAAGTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGGATAAAA
TGGGTGCCACTATTGCCCAAGATTCTTTTACTTTTGAAACAGCTACGGCTCACGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACATCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGACCGCCTATTTCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAATGTTTGAAAATAATAATGAATGTCCCATTTCGCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTCTGAAAAGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.942

97.571

0.526
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.837

99.595

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.652

100

0.377
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.652

100

0.377

Multiple sequence alignment