Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BSR14_RS00945 Genome accession   NZ_CP018186
Coordinates   165625..166374 (+) Length   249 a.a.
NCBI ID   WP_041817183.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 160625..171374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS00925 (BSR14_00920) - 161640..162380 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  BSR14_RS00930 (BSR14_00925) - 162380..163927 (-) 1548 WP_045771695.1 ABC transporter substrate-binding protein/permease -
  BSR14_RS00935 (BSR14_00930) - 164133..164987 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  BSR14_RS00940 (BSR14_00935) - 165047..165418 (-) 372 WP_013989973.1 DUF3021 family protein -
  BSR14_RS00945 (BSR14_00940) mecA 165625..166374 (+) 750 WP_041817183.1 adaptor protein MecA Regulator
  BSR14_RS00950 (BSR14_00945) - 166378..167535 (+) 1158 WP_045771696.1 glycosyltransferase family 4 protein -
  BSR14_RS00955 (BSR14_00950) sufC 167697..168467 (+) 771 WP_045771697.1 Fe-S cluster assembly ATPase SufC -
  BSR14_RS00960 (BSR14_00955) sufD 168504..169766 (+) 1263 WP_002886437.1 Fe-S cluster assembly protein SufD -
  BSR14_RS00965 (BSR14_00960) - 169820..171052 (+) 1233 WP_156209407.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29100.68 Da        Isoelectric Point: 4.0217

>NTDB_id=206755 BSR14_RS00945 WP_041817183.1 165625..166374(+) (mecA) [Streptococcus salivarius strain ICDC1]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLAEEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=206755 BSR14_RS00945 WP_041817183.1 165625..166374(+) (mecA) [Streptococcus salivarius strain ICDC1]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTAAAGGCTCT
TGAGGGTAATTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTTGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAAGCTATGACAGAGCCTACTAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGATTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGAAGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

59.836

97.992

0.586
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment