Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BP422_RS17085 Genome accession   NZ_CP018145
Coordinates   3653043..3653321 (+) Length   92 a.a.
NCBI ID   WP_007721243.1    Uniprot ID   J2GYM8
Organism   Brevibacillus formosus strain NF2     
Function   repress competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3648597..3653030 3653043..3653321 flank 13


Gene organization within MGE regions


Location: 3648597..3653321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BP422_RS17060 (BP422_16645) - 3648597..3649130 (-) 534 WP_088908729.1 PadR family transcriptional regulator -
  BP422_RS32170 - 3649581..3649784 (+) 204 Protein_3389 trypsin-like peptidase domain-containing protein -
  BP422_RS17070 (BP422_16655) - 3649849..3650943 (-) 1095 WP_088908730.1 YheC/YheD family protein -
  BP422_RS17075 (BP422_16660) - 3651146..3651466 (+) 321 WP_088908731.1 winged helix-turn-helix transcriptional regulator -
  BP422_RS17080 (BP422_16665) - 3651579..3653030 (+) 1452 WP_088908732.1 recombinase family protein -
  BP422_RS17085 (BP422_16670) htrA 3653043..3653321 (+) 279 WP_007721243.1 S1C family serine protease Regulator

Sequence

Protein


Download         Length: 92 a.a.        Molecular weight: 9771.26 Da        Isoelectric Point: 6.1950

>NTDB_id=206374 BP422_RS17085 WP_007721243.1 3653043..3653321(+) (htrA) [Brevibacillus formosus strain NF2]
MATGGSPLGLENSVTAGIISAKNRRLQVAKRMYEEIFQTDAAINPGNSGGPLINLNGEVVGLNAFIIQSSQCLGFAIGID
ALKMQLEQYVFK

Nucleotide


Download         Length: 279 bp        

>NTDB_id=206374 BP422_RS17085 WP_007721243.1 3653043..3653321(+) (htrA) [Brevibacillus formosus strain NF2]
ATGGCGACAGGTGGTTCCCCACTTGGTTTGGAAAATTCTGTGACAGCGGGAATCATCAGTGCCAAAAACCGCCGCCTACA
GGTTGCGAAGCGAATGTACGAAGAAATTTTTCAGACGGATGCTGCGATTAACCCTGGAAATAGCGGAGGTCCACTCATTA
ATTTGAATGGGGAAGTCGTTGGTCTCAATGCATTCATCATTCAATCCAGCCAATGCTTGGGCTTCGCCATCGGGATTGAC
GCCCTCAAAATGCAACTGGAGCAGTACGTATTCAAGTGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(5-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J2GYM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

46.939

100

0.5
  htrA Streptococcus pneumoniae Rx1

45.918

100

0.489
  htrA Streptococcus pneumoniae D39

45.918

100

0.489
  htrA Streptococcus pneumoniae R6

45.918

100

0.489
  htrA Streptococcus pneumoniae TIGR4

45.918

100

0.489
  htrA Streptococcus mutans UA159

47.727

95.652

0.457
  htrA Streptococcus gordonii str. Challis substr. CH1

41.237

100

0.435

Multiple sequence alignment