Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   BOC71_RS04945 Genome accession   NZ_CP018137
Coordinates   906582..907286 (+) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain SP61     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 901582..912286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BOC71_RS04925 (BOC71_00923) coaC 901871..902422 (-) 552 WP_001284130.1 phosphopantothenoylcysteine decarboxylase -
  BOC71_RS04930 (BOC71_00924) coaB 902434..903123 (-) 690 WP_000699489.1 phosphopantothenate--cysteine ligase -
  BOC71_RS04935 (BOC71_00925) - 903353..905023 (+) 1671 WP_000845287.1 formate--tetrahydrofolate ligase -
  BOC71_RS04940 (BOC71_00926) mutY 905352..906527 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  BOC71_RS04945 (BOC71_00927) micA 906582..907286 (+) 705 WP_000722076.1 response regulator YycF Regulator
  BOC71_RS04950 (BOC71_00928) micB 907279..908628 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BOC71_RS04955 (BOC71_00929) vicX 908630..909439 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  BOC71_RS04960 (BOC71_00930) relB 909530..909772 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  BOC71_RS04965 (BOC71_00931) - 909774..910028 (+) 255 WP_001823353.1 type II toxin-antitoxin system RelE family toxin -
  BOC71_RS04970 (BOC71_00932) - 910075..910848 (+) 774 WP_000731129.1 potassium channel family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=206128 BOC71_RS04945 WP_000722076.1 906582..907286(+) (micA) [Streptococcus pneumoniae strain SP61]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=206128 BOC71_RS04945 WP_000722076.1 906582..907286(+) (micA) [Streptococcus pneumoniae strain SP61]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment