Detailed information NTG0204459

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: BL295_RS10440
• Genome accession: NZ_CP017954
• Coordinates: 2140781..2142931 (-)
• Length: 716 a.a.
• NCBI ID: WP_071542788.1
• Uniprot ID: D5KLX2
• Organism: Lactiplantibacillus plantarum strain C410L1
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2135781..2147931

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BL295_RS10410	-	2135919..2136211 (-)	293	Protein_1989	type II toxin-antitoxin system RelE/ParE family toxin	-
BL295_RS10415 (BL295_10165)	-	2136327..2137013 (-)	687	WP_003646477.1	CPBP family intramembrane glutamic endopeptidase	-
BL295_RS10420 (BL295_10170)	-	2137107..2137787 (-)	681	WP_071542787.1	CPBP family intramembrane glutamic endopeptidase	-
BL295_RS10425 (BL295_10175)	-	2137874..2138542 (-)	669	WP_003646475.1	CPBP family intramembrane glutamic endopeptidase	-
BL295_RS10430 (BL295_10180)	-	2138610..2139299 (-)	690	WP_003646474.1	CPBP family intramembrane glutamic endopeptidase	-
BL295_RS10435 (BL295_10185)	-	2139389..2140765 (-)	1377	WP_003646473.1	HlyD family secretion protein	-
BL295_RS10440 (BL295_10190)	comA	2140781..2142931 (-)	2151	WP_071542788.1	peptide cleavage/export ABC transporter	Regulator
BL295_RS10445 (BL295_10195)	-	2143198..2143362 (+)	165	Protein_1996	bacteriocin	-
BL295_RS10450 (BL295_10200)	plnF	2143387..2143545 (+)	159	WP_003643811.1	two-peptide bacteriocin plantaricin EF subunit PlnF	-
BL295_RS17550	-	2143917..2144417 (+)	501	WP_225351141.1	CPBP family intramembrane glutamic endopeptidase	-
BL295_RS10460 (BL295_10210)	-	2144718..2145461 (-)	744	WP_016526896.1	response regulator transcription factor	-
BL295_RS10465 (BL295_10215)	-	2145462..2146142 (-)	681	WP_225870361.1	sensor histidine kinase	-
BL295_RS10470 (BL295_10220)	-	2146346..2147521 (-)	1176	WP_016526894.1	IS256 family transposase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80000.71 Da
• Isoelectric Point: 6.6530

>NTDB_id=204459 BL295_RS10440 WP_071542788.1 2140781..2142931(-) (comA) [Lactiplantibacillus plantarum strain C410L1]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFDVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKFLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMVMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide

• Length: 2151 bp

>NTDB_id=204459 BL295_RS10440 WP_071542788.1 2140781..2142931(-) (comA) [Lactiplantibacillus plantarum strain C410L1]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGATGTCCAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTTGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCAGTGGTGGCCATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCAAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAAAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTCCTTATTGATTTTTATCAAC
CAAATAGTGGTGATGTCATATTGAACGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGTCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAAAAACAATTAATCGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• Peptidase C39 family (Peptidase_C39) (5-140)

• ABC transporter (ABC_tran) (498-648)

3D structure

• AlphaFold DB: D5KLX2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	59.046	99.581	0.588
comA	Streptococcus pneumoniae D39	58.766	99.581	0.585
comA	Streptococcus pneumoniae R6	58.766	99.581	0.585
comA	Streptococcus pneumoniae Rx1	58.766	99.581	0.585
comA	Streptococcus pneumoniae TIGR4	58.626	99.581	0.584
comA	Streptococcus mitis SK321	58.485	99.581	0.582
comA	Streptococcus gordonii str. Challis substr. CH1	57.242	100	0.574
comA/nlmT	Streptococcus mutans UA159	54.596	100	0.547