Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   SMA_1903 Genome accession   HE613569
Coordinates   1847053..1847367 (-) Length   104 a.a.
NCBI ID   CCF03194.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1842053..1852367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_1898 rmuC 1842784..1844058 (-) 1275 CCF03189.1 DNA recombination protein RmuC -
  SMA_1899 thiN 1844060..1844689 (-) 630 CCF03190.1 Thiamin pyrophosphokinase -
  SMA_1900 rpe 1844686..1845345 (-) 660 CCF03191.1 Ribulose-phosphate 3-epimerase -
  SMA_1901 - 1845352..1846224 (-) 873 CCF03192.1 Ribosome small subunit-stimulated GTPase EngC -
  SMA_1902 - 1846666..1846923 (-) 258 CCF03193.1 Hypothetical protein -
  SMA_1903 comD/comD3 1847053..1847367 (-) 315 CCF03194.1 Histidine kinase of the competence regulon ComD Regulator
  SMA_1904 - 1847499..1847645 (-) 147 CCF03195.1 Hypothetical protein -
  SMA_1905 - 1847941..1848252 (-) 312 CCF03196.1 Conserved hypothetical protein -
  SMA_1906 - 1848264..1848413 (-) 150 CCF03197.1 Hypothetical protein -
  SMA_1907 - 1848423..1848602 (-) 180 CCF03198.1 Hypothetical protein -
  SMA_1908 - 1848544..1848723 (-) 180 CCF03199.1 Hypothetical protein -
  SMA_1909 - 1848944..1849084 (+) 141 CCF03200.1 Hypothetical protein -
  SMA_1910 - 1849102..1850409 (-) 1308 CCF03201.1 Histidine kinase of the competence regulon ComD -
  SMA_1911 comE/comE1 1850417..1851148 (-) 732 CCF03202.1 Response regulator of the competence regulon ComE Regulator
  SMA_1912 - 1851165..1851491 (-) 327 CCF03203.1 BlpS protein -

Sequence

Protein


Download         Length: 104 a.a.        Molecular weight: 11830.29 Da        Isoelectric Point: 4.7868

>NTDB_id=20368 SMA_1903 CCF03194.1 1847053..1847367(-) (comD/comD3) [Streptococcus macedonicus ACA-DC 198]
MDCFEIPRITYIHSLAILFDNRIEATVLSDVPKISVANFYQDDNFVFMIENSTKEDSIPIDNVNQKGYSSKGNNRGIGLA
TVIEFHQEYGKLPIETSSSNHLFR

Nucleotide


Download         Length: 315 bp        

>NTDB_id=20368 SMA_1903 CCF03194.1 1847053..1847367(-) (comD/comD3) [Streptococcus macedonicus ACA-DC 198]
ATGGATTGTTTCGAAATTCCACGTATTACCTACATTCATAGCCTTGCTATTCTGTTTGATAATAGGATTGAAGCTACAGT
ATTATCAGATGTTCCTAAAATATCCGTAGCGAATTTTTATCAAGATGATAACTTTGTTTTTATGATTGAAAATTCAACCA
AAGAAGATAGTATTCCGATTGATAACGTTAATCAAAAAGGCTATTCAAGCAAAGGTAATAATCGTGGTATTGGCTTAGCA
ACAGTTATTGAATTTCATCAAGAATATGGCAAGCTACCCATTGAAACAAGCAGCTCAAATCACCTCTTTAGATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(13-103)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

57.576

95.192

0.548
  comD/comD2 Streptococcus equinus JB1

56.122

94.231

0.529
  comD/comD1 Streptococcus equinus JB1

47.959

94.231

0.452
  comD/blpH Streptococcus mutans UA159

43

96.154

0.413

Multiple sequence alignment