Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   SMA_1911 Genome accession   HE613569
Coordinates   1850417..1851148 (-) Length   243 a.a.
NCBI ID   CCF03202.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1845417..1856148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_1902 - 1846666..1846923 (-) 258 CCF03193.1 Hypothetical protein -
  SMA_1903 comD/comD3 1847053..1847367 (-) 315 CCF03194.1 Histidine kinase of the competence regulon ComD Regulator
  SMA_1904 - 1847499..1847645 (-) 147 CCF03195.1 Hypothetical protein -
  SMA_1905 - 1847941..1848252 (-) 312 CCF03196.1 Conserved hypothetical protein -
  SMA_1906 - 1848264..1848413 (-) 150 CCF03197.1 Hypothetical protein -
  SMA_1907 - 1848423..1848602 (-) 180 CCF03198.1 Hypothetical protein -
  SMA_1908 - 1848544..1848723 (-) 180 CCF03199.1 Hypothetical protein -
  SMA_1909 - 1848944..1849084 (+) 141 CCF03200.1 Hypothetical protein -
  SMA_1910 - 1849102..1850409 (-) 1308 CCF03201.1 Histidine kinase of the competence regulon ComD -
  SMA_1911 comE/comE1 1850417..1851148 (-) 732 CCF03202.1 Response regulator of the competence regulon ComE Regulator
  SMA_1912 - 1851165..1851491 (-) 327 CCF03203.1 BlpS protein -
  SMA_1913 nisX1 1851651..1852505 (-) 855 CCF03204.1 Transposase -
  SMA_1914 - 1852502..1852762 (-) 261 CCF03205.1 Transposase -
  SMA_1915 - 1852920..1853051 (-) 132 CCF03206.1 Hypothetical protein -
  SMA_1916 - 1853159..1853266 (-) 108 Protein_1915 Hypothetical protein -
  SMA_1917 - 1853573..1854742 (-) 1170 CCF03208.1 Multidrug-efflux transporter -
  SMA_1918 - 1854735..1855790 (-) 1056 CCF03209.1 MccB-like protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28432.53 Da        Isoelectric Point: 5.4372

>NTDB_id=20369 SMA_1911 CCF03202.1 1850417..1851148(-) (comE/comE1) [Streptococcus macedonicus ACA-DC 198]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYQRIEVFSSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRVLYSDIL
YFETSPAVHRVILHTKNERVEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDRATRSVYFETGDTCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=20369 SMA_1911 CCF03202.1 1850417..1851148(-) (comE/comE1) [Streptococcus macedonicus ACA-DC 198]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCAGAGAATAGAGGTGTTTAGTTCTGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCTATTCGTGAAAAA
GATGCAACAGCTATCATTGTTTTTGTAACAACTCATTCAGAATTTATGCTGCTGACCTACCAAGCGTTAGTAGGGGCAAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCAATGAAACATC
AAAATGATAATTTCGGCGAAAATTCTTTTTTATTTGAAACTCCTAAAGCACGTGTGCGCGTTCTATATAGTGACATTCTT
TATTTCGAAACATCTCCTGCCGTGCACCGCGTGATTTTGCATACGAAAAATGAAAGAGTGGAATTTTATGCGACGATTGC
AGAGATTGCTAAATCAGACAAACGTCTTTTCAAGTGTCACCGTTCTTTTATCATTAATGTGGATAATGTGGTTAGATTTG
ATAGAGCGACACGAAGTGTTTATTTCGAAACTGGGGACACTTGCCTAGTTTCTAGAGATAAAATAAAACCTCTATTAAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-238)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

72.016

100

0.72
  comE/blpR Streptococcus mutans UA159

48.954

98.354

0.481
  comE/comE2 Streptococcus equinus JB1

46.281

99.588

0.461

Multiple sequence alignment