Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SMA_1064 Genome accession   HE613569
Coordinates   1045055..1046395 (-) Length   446 a.a.
NCBI ID   CCF02355.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1040055..1051395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_1058 - 1040559..1041623 (-) 1065 CCF02349.1 Nucleoside-binding protein -
  SMA_1059 deoC 1041812..1042474 (-) 663 CCF02350.1 Deoxyribose-phosphate aldolase -
  SMA_1060 - 1042705..1042821 (-) 117 CCF02351.1 Hypothetical protein -
  SMA_1061 - 1042965..1043558 (-) 594 CCF02352.1 Ribosomal RNA small subunit methyltransferase C -
  SMA_1062 coaA 1043672..1044592 (+) 921 CCF02353.1 Pantothenate kinase -
  SMA_1063 rpsT 1044682..1044918 (+) 237 CCF02354.1 SSU ribosomal protein S20p -
  SMA_1064 ciaH 1045055..1046395 (-) 1341 CCF02355.1 Two component system sensor histidine kinase CiaH Regulator
  SMA_1065 ciaR 1046385..1047059 (-) 675 CCF02356.1 Two component system response regulator CiaR Regulator
  SMA_1066 pepN 1047257..1049800 (-) 2544 CCF02357.1 Lysyl aminopeptidase -
  SMA_1067 - 1049973..1050077 (-) 105 Protein_1066 Hypothetical protein -
  SMA_1068 tnpA 1050101..1051357 (+) 1257 CCF02359.1 putative transposase -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50245.17 Da        Isoelectric Point: 6.2742

>NTDB_id=20352 SMA_1064 CCF02355.1 1045055..1046395(-) (ciaH) [Streptococcus macedonicus ACA-DC 198]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNANDYVVRTMERSDTLQSNDSPTD
TFSGGTSSSGKAKPSTSRIGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEGSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKTFVENASHELRTP
LTVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPPTFNEIFENYDMIAEENG
KTFVGHNLVDRPIKSDRTLLKQLMTILFDNAIKYTDNDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=20352 SMA_1064 CCF02355.1 1045055..1046395(-) (ciaH) [Streptococcus macedonicus ACA-DC 198]
ATGTTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTCACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGAATGATTCTCCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACCAGCAGAATTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGGTAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAAACCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTACTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTTTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGATGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCACCGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGTAGACCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACAATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGTCCAGGAATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTCCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.045

99.327

0.596
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment