Detailed information NTG0020339

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: SMA_0461
• Genome accession: HE613569
• Coordinates: 472656..474572 (+)
• Length: 638 a.a.
• NCBI ID: CCF01752.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 467656..479572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_0458	-	469619..470569 (+)	951	Protein_457	Methionyl-tRNA formyltransferase	-
SMA_0459	rsmB	470559..471881 (+)	1323	CCF01750.1	Ribosomal RNA small subunit methyltransferase B	-
SMA_0460	-	471919..472656 (+)	738	CCF01751.1	Protein serine/threonine phosphatase PrpC, regulation of stationary phase	-
SMA_0461	pknB	472656..474572 (+)	1917	CCF01752.1	Serine/threonine protein kinase PrkC, regulator of stationary phase	Regulator
SMA_0462	-	474683..475378 (+)	696	CCF01753.1	Transporter associated with VraSR	-
SMA_0463	vraS	475375..476400 (+)	1026	CCF01754.1	Sensor histidine kinase VraS	-
SMA_0464	-	476384..477028 (+)	645	CCF01755.1	Two component transcriptional regulator VraR	-
SMA_0465	ppiB	477147..478547 (+)	1401	CCF01756.1	Streptococcal lipoprotein rotamase A; Peptidyl-prolyl cis-trans isomerase	-
SMA_0466	yugI	478547..478903 (+)	357	CCF01757.1	General stress protein 13	-

Sequence

Protein

• Length: 638 a.a.
• Molecular weight: 68997.08 Da
• Isoelectric Point: 4.9116

>NTDB_id=20339 SMA_0461 CCF01752.1 472656..474572(+) (pknB) [Streptococcus macedonicus ACA-DC 198]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALFYNRSREPKLVFEDTENTKTLPKVTTSTSVPSTTEQLLKKQKAAKED
KAATENKATKAKTKKKKSHRMFGTLMKIFFAVVIVAIAIFTYLTLTSPSTVSVPDVAGSSLSEAKTTIKSSGLKVGTVHE
VSSDTVESGYVIKTSPTAGSSKKEGSSIDIYVSKGLSGFKIKDYTGQDYQTAVKDLVNNYGVSESQIEIEEVSTSDYDEG
VIISQTPSEGGTFKVSGDDKITFKVATESTVTMPNLTGYTYSEAIAALTALGVSSSHITAYQANPNSSTGYVQVSSPSST
ATVTAQTPYYGDTLSDNVVLYLAADEEESSQAPSSSSSESSESKESSSSSSESSESKESSSSSSSTDDSSSSTETSDE

Nucleotide

• Length: 1917 bp

>NTDB_id=20339 SMA_0461 CCF01752.1 472656..474572(+) (pknB) [Streptococcus macedonicus ACA-DC 198]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTGGCAAAAGATCTCATTCTTGATAATGAAGAAGTTGCCATTAAGGTGCTTCGGACGAATTATCAGACTGATCAAATTG
CCGTAGCGCGTTTCCAACGGGAAGCGCGTGCCATGGCAGAACTGAACCATCCAAATATTGTCTCGATTCGTGATATTGGA
GAAGAAGATGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTAAAAAAATACATTCAAGATCATGCTCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCCTATCTGCGATGACTTTGGCGCATCAACAAGGAATTGTTC
ACCGTGATTTAAAACCACAAAATATATTATTAACCAAAGACGGAACTGTTAAAGTTACTGATTTTGGTATCGCCGTAGCC
TTTGCCGAAACAAGTTTAACGCAAACCAATTCAATGCTAGGTAGTGTGCATTATTTATCGCCTGAACAAGCACGTGGTTC
AAAAGCGACTGTTCAAAGTGATATTTACGCTATGGGGATTATGTTGTTTGAAATGTTAACAGGTCACATCCCATATGATG
GCGATTCAGCTGTTACCATTGCGCTTCAACATTTCCAAAAACCACTTCCTTCCATCATTGATGAGAATAAAAATGTGCCA
CAAGCACTAGAAAATGTTGTTATCAAGGCGACTGCAAAACGTTTAAGTGACCGTTATGCGTCAACTTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTTTTACAACCGTAGCCGTGAACCTAAACTTGTTTTTGAAGATACTGAAAATACAAAGACAC
TTCCAAAGGTAACAACATCAACATCTGTTCCTTCAACGACAGAACAACTTTTGAAGAAACAAAAAGCAGCTAAAGAAGAT
AAAGCAGCAACAGAAAACAAAGCGACTAAAGCTAAAACAAAGAAGAAAAAATCACATCGTATGTTCGGCACGTTAATGAA
AATCTTTTTTGCAGTTGTGATTGTAGCTATTGCTATCTTTACATACTTGACGTTGACCTCACCATCAACCGTGAGTGTTC
CAGATGTTGCTGGCTCTAGTTTATCAGAAGCAAAAACAACGATAAAATCATCAGGTCTTAAAGTTGGAACCGTTCATGAA
GTATCAAGCGATACCGTCGAGAGTGGTTACGTTATTAAGACAAGTCCAACTGCTGGTTCATCGAAAAAAGAAGGGTCATC
AATTGATATTTACGTATCAAAAGGCTTATCAGGATTCAAGATAAAAGACTATACAGGTCAAGATTATCAAACAGCCGTTA
AAGATTTGGTTAATAATTATGGTGTTTCAGAGTCGCAAATTGAGATTGAAGAAGTCTCAACGTCAGATTATGACGAAGGT
GTTATCATCAGTCAAACACCTAGCGAAGGTGGAACCTTTAAGGTAAGTGGTGATGATAAGATTACCTTTAAAGTAGCTAC
TGAGAGTACAGTAACAATGCCGAATTTGACAGGATATACTTATTCAGAAGCTATTGCTGCCCTGACGGCTCTAGGTGTAT
CAAGTTCACATATTACGGCTTATCAAGCCAATCCCAATTCATCTACGGGTTATGTGCAAGTAAGCTCACCATCTTCAACA
GCAACTGTCACTGCTCAGACACCATATTATGGTGATACACTAAGTGATAACGTGGTACTTTACCTAGCAGCTGATGAAGA
AGAAAGCTCACAGGCACCATCGTCATCAAGCTCAGAATCCTCTGAATCAAAAGAATCAAGTTCATCAAGCTCAGAATCCT
CTGAATCAAAAGAATCAAGTTCATCAAGCAGTAGTACAGATGACAGTAGCTCATCGACAGAAACAAGTGATGAATAA

Domains

Predicted by InterproScan.

• PASTA domain (PASTA) (511-580)

• PASTA domain (PASTA) (440-506)

• PASTA domain (PASTA) (371-434)

• Protein kinase domain (Pkinase) (12-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	68.484	92.006	0.63
stkP/pknB	Streptococcus salivarius strain HSISS4	62.421	99.687	0.622
stkP	Streptococcus pneumoniae TIGR4	58.161	83.542	0.486
stkP	Streptococcus pneumoniae D39	57.974	83.542	0.484
stkP	Streptococcus pneumoniae R6	57.974	83.542	0.484
stkP	Streptococcus pneumoniae Rx1	57.786	83.542	0.483