Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SMA_0345 Genome accession   HE613569
Coordinates   355312..356067 (+) Length   251 a.a.
NCBI ID   CCF01636.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 350312..361067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0342 glnP 350720..352291 (-) 1572 CCF01633.1 Amino acid ABC transporter, glutamine-binding protein/permease protein -
  SMA_0343 - 352428..354320 (+) 1893 CCF01634.1 Hypothetical protein -
  SMA_0344 uppP 354372..355211 (+) 840 CCF01635.1 Undecaprenyl-diphosphatase -
  SMA_0345 mecA 355312..356067 (+) 756 CCF01636.1 Negative regulator of genetic competence MecA Regulator
  SMA_0346 tagO 356069..357232 (+) 1164 CCF01637.1 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase -
  SMA_0347 sufC 357345..358115 (+) 771 CCF01638.1 Iron-sulfur cluster assembly ATPase protein SufC -
  SMA_0348 sufD 358189..359451 (+) 1263 CCF01639.1 Iron-sulfur cluster assembly protein SufD -
  SMA_0349 csd 359453..360685 (+) 1233 CCF01640.1 Cysteine desulfurase, SufS subfamily -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28850.66 Da        Isoelectric Point: 4.0627

>NTDB_id=20333 SMA_0345 CCF01636.1 355312..356067(+) (mecA) [Streptococcus macedonicus ACA-DC 198]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSIMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMISKGDTEAHEKLGKIEEMMEGAVEDVLTEQVQAEPTEEDINPSDYVHYV
LDFPTLEAVVSFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVTKLKMIELI

Nucleotide


Download         Length: 756 bp        

>NTDB_id=20333 SMA_0345 CCF01636.1 355312..356067(+) (mecA) [Streptococcus macedonicus ACA-DC 198]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATCTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAATAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTAACGCCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATT
AATAAAGAAATTAACTTTGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGATTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATTGAAGAAATGATGGAAGGTGCTG
TTGAGGATGTTCTCACAGAACAAGTTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTATCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGTGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTACAAAATTAAAAATGATTGAGTTGATATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.935

98.805

0.661
  mecA Streptococcus thermophilus LMD-9

59.514

98.406

0.586
  mecA Streptococcus thermophilus LMG 18311

59.109

98.406

0.582
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49

Multiple sequence alignment