Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   DN94_04560 Genome accession   CP007565
Coordinates   878326..879006 (-) Length   226 a.a.
NCBI ID   AHX74974.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain 138spar     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 873326..884006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DN94_04535 - 873523..874296 (-) 774 AHX74969.1 membrane protein -
  DN94_04540 - 874286..874972 (-) 687 AHX74970.1 DNA-binding protein -
  DN94_04545 - 875039..876604 (-) 1566 AHX74971.1 signal recognition particle -
  DN94_04550 - 876622..876954 (-) 333 AHX74972.1 DNA-binding protein -
  DN94_04555 ciaH 877029..878342 (-) 1314 AHX74973.1 histidine kinase Regulator
  DN94_04560 ciaR 878326..879006 (-) 681 AHX74974.1 transcriptional regulator Regulator
  DN94_04565 - 879168..881717 (-) 2550 AHX74975.1 aminopeptidase N -
  DN94_04570 - 881863..882516 (-) 654 AHX74976.1 PhoU family transcriptional regulator -
  DN94_04575 - 882550..883308 (-) 759 AHX74977.1 phosphate ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25852.63 Da        Isoelectric Point: 4.2507

>NTDB_id=20307 DN94_04560 AHX74974.1 878326..879006(-) (ciaR) [Streptococcus agalactiae strain 138spar]
MIKILLIEDDLSLSNSVFDFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=20307 DN94_04560 AHX74974.1 878326..879006(-) (ciaR) [Streptococcus agalactiae strain 138spar]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGCCTTTCCAATTCCGTTTTTGATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGCCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae D39

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae R6

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae Rx1

88.393

99.115

0.876
  ciaR Streptococcus mutans UA159

88.688

97.788

0.867
  vicR Streptococcus mutans UA159

35.193

100

0.363
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.607

99.115

0.363

Multiple sequence alignment