Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DN94_01755 Genome accession   CP007565
Coordinates   298768..299523 (+) Length   251 a.a.
NCBI ID   AHX74490.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain 138spar     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 293768..304523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DN94_01740 - 294207..295757 (-) 1551 AHX74488.1 glutamine ABC transporter substrate-binding protein -
  DN94_01750 - 297809..298648 (+) 840 AHX74489.1 UDP pyrophosphate phosphatase -
  DN94_01755 mecA 298768..299523 (+) 756 AHX74490.1 adapter protein mecA Regulator
  DN94_01760 - 299525..300685 (+) 1161 AHX74491.1 UDP-N-acetylglucosamine:UDP-P N-acetylglucosaminyl-1-P transferase -
  DN94_01765 - 300850..301620 (+) 771 AHX74492.1 iron ABC transporter ATP-binding protein -
  DN94_01770 - 301657..302919 (+) 1263 AHX74493.1 Fe-S cluster assembly protein SufD -
  DN94_01775 - 302921..304153 (+) 1233 AHX74494.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28985.80 Da        Isoelectric Point: 4.1816

>NTDB_id=20283 DN94_01755 AHX74490.1 298768..299523(+) (mecA) [Streptococcus agalactiae strain 138spar]
MEMKQISETTLKITISMEDLEDSGMELKDFLIPQEKTEEFFYSVMDELDLPENFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQPEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=20283 DN94_01755 AHX74490.1 298768..299523(+) (mecA) [Streptococcus agalactiae strain 138spar]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATAGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTTATGGATGAATTAGACTTGCCAGAAAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACCTT
GGAACAATCGATGTTGGAAAAAGGGGATACGGATGCTCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAACCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACCAAGCTACTTTGCTAATTTGATGTACGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.339

98.805

0.665
  mecA Streptococcus thermophilus LMD-9

60.159

100

0.602
  mecA Streptococcus thermophilus LMG 18311

59.363

100

0.594
  mecA Streptococcus pneumoniae Rx1

46.215

100

0.462
  mecA Streptococcus pneumoniae D39

46.215

100

0.462
  mecA Streptococcus pneumoniae R6

46.215

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.215

100

0.462

Multiple sequence alignment