Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SPG_1303 Genome accession   CP001015
Coordinates   1268795..1269532 (-) Length   245 a.a.
NCBI ID   ACF55531.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1263795..1274532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_1300 - 1265299..1266237 (-) 939 ACF56521.1 Peptide methionine sulfoxide reductase -
  SPG_1301 thrB 1266487..1267356 (-) 870 ACF56078.1 homoserine kinase -
  SPG_1302 metM 1267358..1268644 (-) 1287 ACF55841.1 homoserine dehydrogenase -
  SPG_1303 mecA 1268795..1269532 (-) 738 ACF55531.1 adapter protein MecA Regulator
  SPG_1304 - 1269732..1270766 (-) 1035 ACF54906.1 conserved hypothetical protein -
  SPG_1305 - 1270795..1272228 (-) 1434 ACF56165.1 hypothetical protein -
  SPG_1306 - 1272244..1273230 (-) 987 ACF55330.1 glycosyl transferase, group 2 family protein -
  SPG_1307 - 1273232..1274332 (-) 1101 ACF54861.1 glycosyl transferase, group 1 family protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28409.24 Da        Isoelectric Point: 4.0199

>NTDB_id=20200 SPG_1303 ACF55531.1 1268795..1269532(-) (mecA) [Streptococcus pneumoniae G54]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=20200 SPG_1303 ACF55531.1 1268795..1269532(-) (mecA) [Streptococcus pneumoniae G54]
ATGAAAATGAAACAAATTAGTGATACAACTTTAAAAATCACTATGTCTTTAGAGGATTTGATGGATCGTGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGCTAGAGATGCCTGATAGCT
TTCTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTGACCAAGTCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTGCCAGATATGGAAGAATTGGCTCAAATGTCTCCAGATGAATTTAT
CAAAACCCTGGAAAAAAGCATCGCAGACAAAACCAAGGATGATATCGAAGCCATTCAATCTCTTGAGCAAGTTGAAGCCA
AGGAAGAAGAGCAAGAGCAGGCTGAACAAGAAGCTGAGAGTAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTAGTTTTTGCCAAGACAGTGACTTTTGAAATGGAAACTTCTGAACTCTACAAAATGAACGAGCG
CTATTATTTGACCATTTTAGTGGATATTGAAAATCATCCAAGCCCATATCCAGCTTGGCTGTTGGCCCGTATGCGCGAGT
TTGCAGACGATAGTGATATCAGTCGCTCAGTCTTACAAGAGTATGGTCAAGTCTTGATGAGTCACGATGCAGTGCTCAAT
CTGCAAAAAATCGGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

99.184

100

0.992
  mecA Streptococcus pneumoniae D39

99.184

100

0.992
  mecA Streptococcus pneumoniae R6

99.184

100

0.992
  mecA Streptococcus pneumoniae TIGR4

98.776

100

0.988
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.486
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.482
  mecA Streptococcus mutans UA159

48.163

100

0.482

Multiple sequence alignment