Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SPG_0476 Genome accession   CP001015
Coordinates   470205..470942 (+) Length   245 a.a.
NCBI ID   ACF55252.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 465205..475942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_0470 - 466536..466823 (-) 288 ACF55002.1 conserved hypothetical protein -
  SPG_0471 - 466833..467243 (-) 411 ACF55464.1 histidine triad domain -
  SPG_0472 pptA 467311..468042 (+) 732 ACF55022.1 ABC transporter, ATP-binding protein Regulator
  SPG_0473 - 468039..469088 (+) 1050 ACF56550.1 ABC transporter, permease protein -
  SPG_0474 blpT 469256..469585 (-) 330 ACF55843.1 BlpT protein, fusion -
  SPG_0475 blpS 469862..470200 (+) 339 ACF55842.1 BlpS protein -
  SPG_0476 comE/blpR 470205..470942 (+) 738 ACF55252.1 BlpR response regulator TCS13 Regulator
  SPG_0477 blpH 470956..472296 (+) 1341 ACF56847.1 BlpH histidine kinase TCS13 -
  SPG_0478 blpC 472367..472495 (-) 129 ACF56106.1 bacteriocin BlpC -
  SPG_0479 blpB 472552..473913 (-) 1362 ACF56304.1 BlpC ABC transporter -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28760.71 Da        Isoelectric Point: 6.5884

>NTDB_id=20182 SPG_0476 ACF55252.1 470205..470942(+) (comE/blpR) [Streptococcus pneumoniae G54]
MRIFVLEDDFSQQTRIETTXEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INKLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=20182 SPG_0476 ACF55252.1 470205..470942(+) (comE/blpR) [Streptococcus pneumoniae G54]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATNGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCTGAAGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCTTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCTTGTCAGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAGCCCCGTCTCTTGCAGTGCCACCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCCCGTTATAAGGTCAGGGAAGTGTCTGAGGCC
ATCAATAAATTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.909

99.184

0.535
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

37.603

98.776

0.371
  comE Streptococcus infantis strain Atu-4

35.887

100

0.363

Multiple sequence alignment