Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   BKM66_RS03525 Genome accession   NZ_CP017666
Coordinates   708506..710743 (+) Length   745 a.a.
NCBI ID   WP_105183699.1    Uniprot ID   A0AAD0KVV0
Organism   Streptococcus suis strain 0061     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 703506..715743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS03500 (BKM66_03455) - 703575..704504 (-) 930 WP_105183703.1 ABC transporter substrate-binding protein -
  BKM66_RS03505 (BKM66_03460) - 704517..705302 (-) 786 WP_105183702.1 ABC transporter ATP-binding protein -
  BKM66_RS03510 (BKM66_03465) - 705454..706899 (-) 1446 WP_105183701.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  BKM66_RS03515 (BKM66_03470) - 707047..707793 (+) 747 WP_105183700.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  BKM66_RS03520 (BKM66_03475) comEA/celA/cilE 707860..708522 (+) 663 WP_079399194.1 helix-hairpin-helix domain-containing protein Machinery gene
  BKM66_RS03525 (BKM66_03480) comEC/celB 708506..710743 (+) 2238 WP_105183699.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BKM66_RS03535 (BKM66_03485) - 711019..712183 (-) 1165 Protein_636 IS110 family transposase -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83714.27 Da        Isoelectric Point: 6.5622

>NTDB_id=201299 BKM66_RS03525 WP_105183699.1 708506..710743(+) (comEC/celB) [Streptococcus suis strain 0061]
MSRLSKLPCQPIHLAVLAVAAYFAVHSFSLLTMGLLSLLLVVFGFRQGKAVFLKTLPLLALCGLFFGCQKVQWEQAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLASQEEQTYFQNLTGLVQLEVEAEVSLPAGQRNFNGFDYQAYL
KTQGIYRTVKLTVIKRIVPVHSWNIFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVNKLQILFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLVL
PRFPLTAGGVLTFTYAFLLTVFDFEDVGQIKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPVVKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSGLVLLLLLVSLFLLYDFHRKKNWFLGLSLVLALLFFITK
HPLENEVAVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFTAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVDVVAVGDRLPIFDSYLEVLYPDGTGDGGNNDSVVLYGRLL
ETNFLFTGDLEQGELDLVESYPQLPVDVLKAGHHGSQGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=201299 BKM66_RS03525 WP_105183699.1 708506..710743(+) (comEC/celB) [Streptococcus suis strain 0061]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCTTGCTAAGTCTGTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGGCAGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTGTGCGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCAGGCAGCCCAGTCAGCA
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGTGACAGCTTGTCTTTTCGAGGTCGGGC
TGATGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAACAGACTTATTTTCAAAATCTGACAGGTCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAACGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGTGATTAAGAGGATTGTTCCTGTCCATTCTTGGAATATTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCCATGAGCCACTATATGACAG
GGCTCTTGTTTGGGGAGCTGGATAGTGAGTTTGACCAGATGAGCGACCTCTATTCCAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGCTGCGGTTGGGCTTGACCAAGGAAAC
GGTGAATAAATTGCAGATTCTCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTAGTGCGGTCCTTGG
TCCAAAAAATTCTGGGCAATATGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACGGTCTTTGTCTGCCTGCTGGTGCTG
CCCCGATTTCCACTGACAGCAGGTGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATGT
GGGGCAGATCAAAAAGGCTGCGGTGGAGAGTCTCAGTATTTCGCTAGGGATTTTGCCGGTGCTCATGACTTATTTCTATG
CCTTCCAGCCCTTGTCTATCCTCTTGACCTTTGTATTTTCCTTTATCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATAACCTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGGACTGGTTCTCTTGCTCTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAAGAAAAACTGGTTCCTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAATGAGGTGGCGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGTCGGGTCGATTTTACGGCCAAGGAAGCTTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGAACCTTGATCCCTTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGACGCTGAC
CATGTGGGCGATGTGCTGGAAGTGGCAAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCAGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTGATGTGGTGGCGGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAAGTCCTCTATCCAGACGGGACGGGTGACGGTGGCAATAATGACTCTGTTGTTCTTTACGGTCGTTTGCTG
GAAACCAATTTTCTCTTCACAGGTGACTTGGAGCAGGGGGAGTTGGATTTGGTAGAAAGCTATCCGCAGCTACCTGTTGA
TGTCCTCAAAGCTGGTCACCACGGCTCCCAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCTGCAGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGAAATATCCAA
GTCTATCGCACCGACCAGCAAGGAGCTATCCGCTTCCGAGGTTGGAAAGAGTGGAGGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-460)

Domain of unknown function (DUF4131) (DUF4131)

(28-172)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.701

99.732

0.536
  comEC/celB Streptococcus mitis NCTC 12261

52.901

99.463

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

52.022

99.597

0.518
  comEC/celB Streptococcus pneumoniae Rx1

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae D39

51.752

99.597

0.515
  comEC/celB Streptococcus pneumoniae R6

51.752

99.597

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

47.931

100

0.482

Multiple sequence alignment