Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   BKM66_RS03520 Genome accession   NZ_CP017666
Coordinates   707860..708522 (+) Length   220 a.a.
NCBI ID   WP_079399194.1    Uniprot ID   A0A0Z8MB94
Organism   Streptococcus suis strain 0061     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 702860..713522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS03500 (BKM66_03455) - 703575..704504 (-) 930 WP_105183703.1 ABC transporter substrate-binding protein -
  BKM66_RS03505 (BKM66_03460) - 704517..705302 (-) 786 WP_105183702.1 ABC transporter ATP-binding protein -
  BKM66_RS03510 (BKM66_03465) - 705454..706899 (-) 1446 WP_105183701.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  BKM66_RS03515 (BKM66_03470) - 707047..707793 (+) 747 WP_105183700.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  BKM66_RS03520 (BKM66_03475) comEA/celA/cilE 707860..708522 (+) 663 WP_079399194.1 helix-hairpin-helix domain-containing protein Machinery gene
  BKM66_RS03525 (BKM66_03480) comEC/celB 708506..710743 (+) 2238 WP_105183699.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BKM66_RS03535 (BKM66_03485) - 711019..712183 (-) 1165 Protein_636 IS110 family transposase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23472.11 Da        Isoelectric Point: 4.0036

>NTDB_id=201298 BKM66_RS03520 WP_079399194.1 707860..708522(+) (comEA/celA/cilE) [Streptococcus suis strain 0061]
MDTIKTYIEMLKEYKWQIALPAVAGLLLTTFLIFSQPAKSDQTGLPDLPQTEQTSNSSELIEETSTEVSEEPSQLVVDVK
GAVTEPGIYYLDAGSRVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSQEEKNTNLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=201298 BKM66_RS03520 WP_079399194.1 707860..708522(+) (comEA/celA/cilE) [Streptococcus suis strain 0061]
ATGGATACAATCAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAGCAGTTGCAGGTTTGCT
TCTGACCACATTCTTAATATTCAGCCAACCAGCTAAGTCAGATCAAACAGGACTGCCAGATTTACCACAGACCGAACAAA
CTTCTAATAGCTCTGAGTTGATCGAGGAAACCAGTACAGAAGTAAGTGAGGAGCCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCAGTGACAGAGCCTGGTATTTACTATCTTGATGCAGGAAGTCGGGTCAATGACGCGGTTGAGGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGTAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACTAATCTAGTTAAT
CTCAATACGGCGACCGAGGCGGATTTGCAGACCATTTCGGGCATCGGTGCCAAGCGGGCGGCGGACATTATTGCCTACCG
TGAGGCCAACGGCGGCTTCAAGTCGGTGGACGACCTCAACAATGTGTCGGGCATCGGCGACAAGACCATGGAAAGCATCC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8MB94

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.807

100

0.495
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae R6

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.111

100

0.482
  comEA/celA/cilE Streptococcus mitis SK321

45.652

100

0.477
  comEA Streptococcus thermophilus LMD-9

58.025

73.636

0.427
  comEA Bacillus subtilis subsp. subtilis str. 168

40.284

95.909

0.386
  comEA Lactococcus lactis subsp. cremoris KW2

37.327

98.636

0.368

Multiple sequence alignment