Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CGU46_RS28970 Genome accession   NZ_CP022525
Coordinates   6074458..6075129 (-) Length   223 a.a.
NCBI ID   WP_003090494.1    Uniprot ID   A0A0H2ZC88
Organism   Pseudomonas aeruginosa strain Ocean-1175     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 6069458..6080129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGU46_RS28955 (CGU46_28955) - 6070576..6072720 (+) 2145 WP_003090491.1 methyl-accepting chemotaxis protein -
  CGU46_RS33840 - 6072725..6072892 (-) 168 WP_171430717.1 hypothetical protein -
  CGU46_RS28965 (CGU46_28965) carS 6073124..6074461 (-) 1338 WP_094069621.1 two-component system sensor histidine kinase CarS -
  CGU46_RS28970 (CGU46_28970) ciaR 6074458..6075129 (-) 672 WP_003090494.1 two-component system response regulator CarR Regulator
  CGU46_RS28975 (CGU46_28975) - 6075129..6075443 (-) 315 WP_003097704.1 PepSY domain-containing protein -
  CGU46_RS28980 (CGU46_28980) - 6075443..6075751 (-) 309 WP_003090497.1 PepSY domain-containing protein -
  CGU46_RS28985 (CGU46_28985) - 6075966..6077048 (+) 1083 WP_003143813.1 hypothetical protein -
  CGU46_RS28990 (CGU46_28990) - 6077075..6077968 (+) 894 WP_003110080.1 hypothetical protein -
  CGU46_RS28995 (CGU46_28995) - 6077952..6078218 (+) 267 WP_003090500.1 DUF5329 domain-containing protein -
  CGU46_RS29000 (CGU46_29000) - 6078219..6079412 (-) 1194 WP_021264902.1 NnrS family protein -
  CGU46_RS29005 (CGU46_29005) ppyR 6079399..6079656 (-) 258 WP_021264903.1 psl/pyoverdine operon transcriptional regulator PpyR -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24729.20 Da        Isoelectric Point: 5.8445

>NTDB_id=201255 CGU46_RS28970 WP_003090494.1 6074458..6075129(-) (ciaR) [Pseudomonas aeruginosa strain Ocean-1175]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide


Download         Length: 672 bp        

>NTDB_id=201255 CGU46_RS28970 WP_003090494.1 6074458..6075129(-) (ciaR) [Pseudomonas aeruginosa strain Ocean-1175]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAGCCCTACGACCTGATCATTCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGCCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTATCTGACCAAGCCGTTCCATCCGGAAGA
GTTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGTCAGTGCGTGTGCCTGAACGGCGCCGACGTCGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.727

98.655

0.372
  ciaR Streptococcus pneumoniae Rx1

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae D39

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae R6

37.273

98.655

0.368
  ciaR Streptococcus pneumoniae TIGR4

37.273

98.655

0.368
  micA Streptococcus pneumoniae Cp1015

35.683

100

0.363
  vicR Streptococcus mutans UA159

35.526

100

0.363