Detailed information NTG0200707

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: CGZ53_RS06270
• Genome accession: NZ_CP022435
• Coordinates: 1230375..1232633 (-)
• Length: 752 a.a.
• NCBI ID: WP_100912143.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NZ01
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1225375..1237633

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGZ53_RS06245 (CGZ53_06240)	nagB	1225428..1226132 (-)	705	WP_046388175.1	glucosamine-6-phosphate deaminase	-
CGZ53_RS06250 (CGZ53_06245)	queA	1226313..1227341 (+)	1029	WP_012658715.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
CGZ53_RS06255 (CGZ53_06250)	-	1227381..1228421 (-)	1041	WP_037592486.1	serine hydrolase	-
CGZ53_RS06260 (CGZ53_06255)	sodA	1228587..1229195 (-)	609	WP_012658717.1	superoxide dismutase SodA	-
CGZ53_RS06265 (CGZ53_06260)	holA	1229292..1230332 (-)	1041	WP_100912142.1	DNA polymerase III subunit delta	-
CGZ53_RS06270 (CGZ53_06265)	comEC/celB	1230375..1232633 (-)	2259	WP_100912143.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CGZ53_RS06275 (CGZ53_06270)	comEA/celA/cilE	1232614..1233294 (-)	681	WP_012658720.1	helix-hairpin-helix domain-containing protein	Machinery gene
CGZ53_RS06280 (CGZ53_06275)	-	1233357..1234097 (-)	741	WP_012658721.1	lysophospholipid acyltransferase family protein	-
CGZ53_RS06285 (CGZ53_06280)	-	1234220..1235005 (+)	786	WP_046388252.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
CGZ53_RS06290 (CGZ53_06285)	-	1235046..1235315 (+)	270	WP_012658723.1	GIY-YIG nuclease family protein	-
CGZ53_RS06295 (CGZ53_06290)	-	1235337..1237334 (-)	1998	WP_046389518.1	KUP/HAK/KT family potassium transporter	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 86046.35 Da
• Isoelectric Point: 10.0858

>NTDB_id=200707 CGZ53_RS06270 WP_100912143.1 1230375..1232633(-) (comEC/celB) [Streptococcus uberis strain NZ01]
MTSLLTKFFPIPIPQFSLLCLLVFFAVHFPNKISVCLFLSALVVAFKHRALKRNVKLSCLLMLFASYVYFTKSYQESQFR
QEPTRIESVILVPDSVVINGDSLSFKARKGKNHFQIFYQLKNKKEQDFFKKNNQLLQISGSIELKKAERKRYFNGFDYQD
HLKNQGIYRIGRLKEIKSIGVRKAESFFDYLAIWRRYAIVRSQVQFPKPMSDYMTGLLFGYLDKSFSEMTEIYSQLGIIH
LFALSGMQVSFFLNLFRKGLILSWIPRDFYPILELCFSIIYAGLTGYSISVLRSLLQRNLANMGLKGSTNLCLAFLLMFL
ISPFFPLTIGGVLSFVYAFLLTLIPSENTSGLKGKILGLFYLQLATIPFLILFFSTFHPVSIILTLIFSFLFDILILPLL
TFIFLISPVLTGYHLNSLFQMLEKIMVNVVELFPHPIIFGQPPILVFLSLIFIVALIMAFANRKTYLLSFLIIYFFLLKT
ISIPFENEISIVDVGQGDSILLRDKTNKTLLIDVGGTVAFQGKEDWQKRSSNANAERTLIPYLKSRGIKEIDQLLLTHID
TDHVGDLEVVAKSFKIKEILVSEGSLTNSNFVHRLSKLGNPVTVLKVGNSIDIMNGKLYLIYPWKKGDGRNNDSLVLYGK
LLNKSFLFTGDLEKEGEDAILKRYPSMKTDYLKVGHHGSKGSSSNDFLKVLKPKVAFISAGKDNRFHHPHKETLDRLIEN
HVEILRTDQEGTLRLTGTHQWRLERTHPNLDK

Nucleotide

• Length: 2259 bp

>NTDB_id=200707 CGZ53_RS06270 WP_100912143.1 1230375..1232633(-) (comEC/celB) [Streptococcus uberis strain NZ01]
ATGACATCATTATTGACTAAGTTTTTCCCAATTCCCATTCCACAGTTTTCTTTGCTGTGCTTATTGGTCTTTTTTGCTGT
ACATTTCCCAAACAAAATCAGTGTTTGCTTATTCTTATCAGCTTTGGTTGTCGCCTTCAAACATAGGGCATTAAAAAGAA
ATGTAAAGCTTTCTTGTCTTCTTATGTTATTTGCCTCATATGTTTATTTCACCAAATCTTATCAGGAGAGTCAATTCAGG
CAAGAACCAACACGAATCGAATCTGTTATCTTAGTTCCAGATTCTGTTGTTATAAACGGTGATAGTCTATCTTTTAAAGC
AAGAAAAGGAAAAAATCATTTTCAAATTTTTTACCAATTGAAGAACAAAAAAGAGCAAGACTTTTTTAAGAAAAATAATC
AGCTGTTACAAATCAGTGGAAGTATTGAACTCAAAAAAGCTGAGAGGAAACGCTACTTTAATGGTTTTGACTATCAGGAC
CATCTGAAAAATCAAGGAATCTATCGAATTGGTCGTTTGAAAGAGATAAAATCAATTGGCGTTCGAAAAGCTGAAAGTTT
TTTCGATTATTTAGCTATTTGGCGTCGATATGCCATAGTAAGGAGTCAAGTTCAGTTTCCTAAGCCCATGTCTGATTACA
TGACTGGATTATTATTTGGGTATTTGGATAAATCATTCTCTGAGATGACAGAAATTTATAGTCAATTAGGAATCATACAT
CTTTTTGCCTTGTCAGGAATGCAGGTATCCTTCTTTTTAAATCTCTTCCGAAAGGGATTAATCTTAAGTTGGATTCCAAG
AGACTTTTATCCTATTTTAGAATTATGTTTTTCGATTATTTATGCTGGTTTAACAGGTTATAGCATTTCAGTATTAAGAA
GTCTATTGCAGCGAAATTTGGCAAATATGGGTTTGAAAGGAAGTACAAATTTATGCCTGGCTTTTCTCCTAATGTTCTTG
ATATCTCCTTTTTTTCCATTAACCATTGGCGGAGTCTTGTCCTTTGTCTATGCCTTCCTTTTAACTCTCATTCCCTCTGA
AAATACATCAGGATTAAAAGGGAAAATTTTAGGGCTTTTTTACTTACAATTGGCCACTATTCCTTTTTTAATCTTATTTT
TTTCAACATTTCACCCAGTATCAATCATTTTAACACTTATCTTTTCTTTTTTATTCGATATCCTTATTCTTCCCTTGCTT
ACTTTTATTTTTCTAATAAGTCCAGTATTGACCGGTTACCACCTTAACAGTTTATTTCAAATGTTAGAAAAAATCATGGT
AAATGTAGTTGAATTGTTTCCTCATCCGATTATTTTTGGTCAACCACCTATTTTAGTCTTTCTCTCGCTTATCTTTATAG
TTGCATTGATAATGGCTTTTGCTAATCGAAAAACCTATCTCCTGTCATTTTTGATAATTTATTTTTTCCTTTTAAAAACG
ATTTCAATTCCCTTTGAAAATGAGATATCAATTGTGGATGTTGGTCAAGGAGATAGCATTCTTCTGAGAGATAAAACTAA
TAAAACGCTCTTAATTGATGTTGGTGGCACAGTAGCTTTTCAAGGAAAAGAAGATTGGCAAAAAAGAAGCAGCAATGCAA
ATGCAGAAAGAACCTTAATTCCATATTTAAAATCAAGAGGCATTAAAGAAATTGATCAATTACTCTTAACACACATTGAT
ACTGACCATGTTGGAGATTTGGAAGTGGTGGCAAAGTCATTTAAAATAAAAGAGATTCTTGTTAGTGAAGGAAGTTTAAC
AAATAGTAATTTCGTTCATCGTTTGTCAAAATTAGGGAATCCCGTCACCGTCTTAAAAGTTGGTAATAGTATTGATATTA
TGAATGGAAAGCTATACCTCATTTATCCATGGAAAAAGGGAGATGGTCGAAATAATGACTCACTTGTTTTATATGGAAAA
CTCTTAAACAAGTCCTTCCTTTTTACTGGTGATTTAGAAAAGGAAGGAGAAGATGCAATACTAAAAAGATACCCTTCAAT
GAAGACTGATTATTTAAAAGTTGGACATCATGGTTCTAAAGGGTCATCTAGTAACGATTTTCTAAAAGTTCTCAAACCTA
AAGTGGCATTTATTTCGGCGGGAAAAGACAATAGGTTTCATCATCCTCATAAAGAGACCTTAGACAGGCTTATAGAGAAT
CATGTTGAAATACTAAGGACAGATCAAGAGGGGACTCTACGCCTCACAGGGACTCATCAGTGGCGCTTGGAGAGAACGCA
TCCGAATTTAGATAAATAG

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	43.876	98.803	0.434
comEC/celB	Streptococcus mitis NCTC 12261	43.742	98.803	0.432
comEC	Lactococcus lactis subsp. cremoris KW2	42.61	99.867	0.426
comEC/celB	Streptococcus pneumoniae TIGR4	42.992	98.67	0.424
comEC/celB	Streptococcus pneumoniae Rx1	42.857	98.67	0.423
comEC/celB	Streptococcus pneumoniae D39	42.857	98.67	0.423
comEC/celB	Streptococcus pneumoniae R6	42.857	98.67	0.423