Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SDD27957_05615 Genome accession   CM001076
Coordinates   1092487..1093161 (-) Length   224 a.a.
NCBI ID   EFY02768.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1087487..1098161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_05590 - 1087671..1088948 (-) 1278 EFY02763.1 pyrimidine-nucleoside phosphorylase -
  SDD27957_05595 - 1088935..1089567 (-) 633 EFY02764.1 16S rRNA m(2)G 1207 methyltransferase -
  SDD27957_05600 - 1089803..1090723 (+) 921 EFY02765.1 pantothenate kinase -
  SDD27957_05605 rpsT 1090792..1091025 (+) 234 EFY02766.1 30S ribosomal protein S20 -
  SDD27957_05610 ciaH 1091183..1092406 (-) 1224 EFY02767.1 Sensor protein ciaH Regulator
  SDD27957_05615 ciaR 1092487..1093161 (-) 675 EFY02768.1 Transcriptional regulatory protein ciaR Regulator
  SDD27957_05620 - 1093366..1095903 (-) 2538 EFY02769.1 putative lysyl-aminopeptidase -
  SDD27957_05625 - 1096103..1096756 (-) 654 EFY02770.1 phosphate transport system protein -
  SDD27957_05630 - 1096834..1097592 (-) 759 EFY02771.1 phosphate import ATP-binding protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25539.54 Da        Isoelectric Point: 4.4684

>NTDB_id=20041 SDD27957_05615 EFY02768.1 1092487..1093161(-) (ciaR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MLKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGKKEVQVDGQPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDLVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=20041 SDD27957_05615 EFY02768.1 1092487..1093161(-) (ciaR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGCTCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGAGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGTTTTCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCAGTGTTGATCATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAACGTCGTAG
TGGATTTAGGAAAAAAAGAAGTTCAAGTGGATGGCCAACCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATCTTGTGGACAAACTTCAGACATTAA
GAAGTGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae D39

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae R6

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae TIGR4

83.71

98.661

0.826
  ciaR Streptococcus mutans UA159

83.258

98.661

0.821
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379
  vicR Streptococcus mutans UA159

35.443

100

0.375

Multiple sequence alignment