Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SDD27957_02890 Genome accession   CM001076
Coordinates   560023..560733 (+) Length   236 a.a.
NCBI ID   EFY02256.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 555023..565733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_02860 - 555600..555890 (+) 291 EFY02250.1 hypothetical protein -
  SDD27957_02865 - 556145..556561 (+) 417 EFY02251.1 Transposase -
  SDD27957_02870 - 556794..557441 (-) 648 EFY02252.1 hypothetical protein -
  SDD27957_02875 - 557456..558157 (-) 702 EFY02253.1 amino acid ABC transporter, permease protein -
  SDD27957_02880 - 558171..558971 (-) 801 EFY02254.1 glutamine-binding protein precursor -
  SDD27957_02885 - 558971..559765 (-) 795 EFY02255.1 glutamine transporter, ATP-binding protein 4 -
  SDD27957_02890 vicR 560023..560733 (+) 711 EFY02256.1 Two-component response regulator Regulator
  SDD27957_02895 vicK 560726..562078 (+) 1353 EFY02257.1 sensor histidine kinase Regulator
  SDD27957_02910 rnc 562989..563681 (+) 693 EFY02258.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=20030 SDD27957_02890 EFY02256.1 560023..560733(+) (vicR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=20030 SDD27957_02890 EFY02256.1 560023..560733(+) (vicR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGAAAAAAATACTGATTGTGGATGATGAGAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGAGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAAGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACTATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTGGACGTGACAGTTCGCCGCCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment