Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SDD27957_00230 Genome accession   CM001076
Coordinates   58888..59799 (+) Length   303 a.a.
NCBI ID   EFY01754.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53888..64799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_00210 - 54367..55629 (+) 1263 EFY01750.1 phosphoribosylamine--glycine ligase -
  SDD27957_00215 - 55884..56372 (+) 489 EFY01751.1 phosphoribosylaminoimidazole carboxylase catalytic subunit -
  SDD27957_00220 - 56359..57444 (+) 1086 EFY01752.1 phosphoribosylaminoimidazole carboxylase ATPase subunit -
  SDD27957_00225 - 57454..58746 (+) 1293 EFY01753.1 adenylosuccinate lyase -
  SDD27957_00230 comR 58888..59799 (+) 912 EFY01754.1 Transcriptional regulator Regulator
  SDD27957_00235 comS 59886..59978 (+) 93 EFY01755.1 hypothetical protein Regulator
  SDD27957_00240 ruvB 60032..61030 (+) 999 EFY01756.1 Holliday junction DNA helicase RuvB -
  SDD27957_00245 - 61165..61596 (+) 432 EFY01757.1 protein tyrosine phosphatase -
  SDD27957_00250 - 61625..62026 (+) 402 EFY01758.1 hypothetical protein -
  SDD27957_00255 - 62023..63798 (+) 1776 EFY01759.1 acyltransferase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35627.22 Da        Isoelectric Point: 4.5798

>NTDB_id=20007 SDD27957_00230 EFY01754.1 58888..59799(+) (comR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=20007 SDD27957_00230 EFY01754.1 58888..59799(+) (comR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTATGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCAAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGGAAATTGCAAGTCCGAGAGTCTCAGTTTGATGAGATATTCGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTGAGTG
AAAACATCAATTTTGGTGTTGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAGCTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATTCAGGATTGGAATAGAATGCCTATACTAAAATTAATAGAATGGAAGTACTTTTTAATAAAGCAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAGATAACAGGAGACAAGTATTTGGAAGAGCAATTAATTA
AAGAATGGGAGAAAGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(12-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

82.838

100

0.828
  comR Streptococcus pyogenes MGAS315

55.333

99.01

0.548
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

50.847

97.36

0.495
  comR Streptococcus mutans UA159

49.164

98.68

0.485

Multiple sequence alignment