Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   - Genome accession   CM001076
Coordinates   59886..59978 (+) Length   31 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 54886..64978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_00215 - 55884..56372 (+) 489 EFY01751.1 phosphoribosylaminoimidazole carboxylase catalytic subunit -
  SDD27957_00220 - 56359..57444 (+) 1086 EFY01752.1 phosphoribosylaminoimidazole carboxylase ATPase subunit -
  SDD27957_00225 - 57454..58746 (+) 1293 EFY01753.1 adenylosuccinate lyase -
  SDD27957_00230 comR 58888..59799 (+) 912 EFY01754.1 Transcriptional regulator Regulator
  SDD27957_00235 comS 59886..59978 (+) 93 EFY01755.1 hypothetical protein Regulator
  SDD27957_00240 ruvB 60032..61030 (+) 999 EFY01756.1 Holliday junction DNA helicase RuvB -
  SDD27957_00245 - 61165..61596 (+) 432 EFY01757.1 protein tyrosine phosphatase -
  SDD27957_00250 - 61625..62026 (+) 402 EFY01758.1 hypothetical protein -
  SDD27957_00255 - 62023..63798 (+) 1776 EFY01759.1 acyltransferase -

Sequence

Protein


Download         Length: 31 a.a.        Molecular weight: 3901.71 Da        Isoelectric Point: 10.0999

>NTDB_id=574 59886..59978(+) (comS) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MFKKYHYYFILTAMLAFKAAQMISQVDWWRL

Nucleotide


Download         Length: 93 bp        

>NTDB_id=574 59886..59978(+) (comS) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGTTCAAAAAATATCACTACTATTTTATACTTACTGCTATGTTGGCATTTAAAGCAGCTCAGATGATAAGTCAAGTGGA
TTGGTGGCGTTTG

XIP

This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

QVDWWRL


Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

64.516

100

0.645
  comS Streptococcus pyogenes MGAS315

41.935

100

0.419

Multiple sequence alignment