Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   WH25_RS09330 Genome accession   NZ_CP017295
Coordinates   1949164..1949892 (-) Length   242 a.a.
NCBI ID   WP_046164602.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1944164..1954892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS09310 (WH25_09310) - 1944571..1945803 (-) 1233 WP_046164598.1 cysteine desulfurase -
  WH25_RS09315 (WH25_09315) sufD 1945843..1947105 (-) 1263 WP_046164599.1 Fe-S cluster assembly protein SufD -
  WH25_RS09320 (WH25_09320) sufC 1947147..1947917 (-) 771 WP_046164600.1 Fe-S cluster assembly ATPase SufC -
  WH25_RS09325 (WH25_09325) - 1948004..1949170 (-) 1167 WP_046164601.1 glycosyltransferase family 4 protein -
  WH25_RS09330 (WH25_09330) mecA 1949164..1949892 (-) 729 WP_046164602.1 adaptor protein MecA Regulator
  WH25_RS09335 (WH25_09335) - 1950014..1950862 (-) 849 WP_008809637.1 undecaprenyl-diphosphate phosphatase -
  WH25_RS09340 (WH25_09340) - 1950951..1952870 (-) 1920 WP_046164749.1 DUF2207 domain-containing protein -
  WH25_RS09345 (WH25_09345) - 1953167..1954732 (+) 1566 WP_046164603.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28295.98 Da        Isoelectric Point: 4.2042

>NTDB_id=197439 WH25_RS09330 WP_046164602.1 1949164..1949892(-) (mecA) [Streptococcus gordonii strain IE35]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPNMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDASEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTIHYPVDTSELYKMDQHYYLTILVDIEGRPSRYPAWLLAAMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=197439 WH25_RS09330 WP_046164602.1 1949164..1949892(-) (mecA) [Streptococcus gordonii strain IE35]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATTAAGATCACAATTAAATTAGAAGATCTAGAAGAGCACGGCATGGAGAT
GGCAGATTTTCTGGTTCCTCAGGAAAAGACGGAGGAATTTTTCTATACCATTTTAGATGAACTCGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GATAAAAATTTGAATTTTGAAGATTTGGCTGACTTGCCTAATATGGACGAACTGTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAAAGCCGTGATGATATAGATGCTGTTCAAATGCTGGAAAAAGCAGAAGAGG
AAGATGCATCTGAGCCAGAGGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAT
CTGATCGCTTTCACCAAGACTATCCACTATCCAGTTGATACATCAGAGCTATACAAGATGGATCAGCATTACTATTTGAC
TATTCTAGTAGATATTGAAGGTCGTCCGAGTCGTTATCCTGCTTGGCTTCTGGCAGCAATGCGTGAACATGCTGAGGATA
CAGATACGACGAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

64.898

100

0.657
  mecA Streptococcus pneumoniae D39

64.898

100

0.657
  mecA Streptococcus pneumoniae R6

64.898

100

0.657
  mecA Streptococcus pneumoniae TIGR4

64.898

100

0.657
  mecA Streptococcus mutans UA159

51.029

100

0.512
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.488

Multiple sequence alignment