Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   WH25_RS03870 Genome accession   NZ_CP017295
Coordinates   811702..813549 (+) Length   615 a.a.
NCBI ID   WP_046165167.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 806702..818549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS03855 (WH25_03855) fmt 808706..809641 (+) 936 WP_046165165.1 methionyl-tRNA formyltransferase -
  WH25_RS03860 (WH25_03860) rsmB 809631..810944 (+) 1314 WP_046165166.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  WH25_RS03865 (WH25_03865) - 810965..811705 (+) 741 WP_045506058.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  WH25_RS03870 (WH25_03870) stkP 811702..813549 (+) 1848 WP_046165167.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  WH25_RS03875 (WH25_03875) liaF 813725..814423 (+) 699 WP_046165201.1 cell wall-active antibiotics response protein LiaF -
  WH25_RS03880 (WH25_03880) - 814420..815421 (+) 1002 WP_046165168.1 sensor histidine kinase -
  WH25_RS03885 (WH25_03885) - 815423..816055 (+) 633 WP_046165169.1 response regulator transcription factor -
  WH25_RS03890 (WH25_03890) - 816143..817546 (+) 1404 WP_046165170.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  WH25_RS03895 (WH25_03895) - 817543..817929 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 66872.91 Da        Isoelectric Point: 6.5896

>NTDB_id=197406 WH25_RS03870 WP_046165167.1 811702..813549(+) (stkP) [Streptococcus gordonii strain IE35]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRVTDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHARGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENANVP
QSLENVIIKATAKKLTDRYQSVSDMYVDLSSCLSPERRNEKKLMFDDAVKADTKTLPKIPQVTPPVASRVNNDPATDVEQ
KVPQVAPPTKPKKKHHLRARYKVLLAAVFLVIAAFLALLYLTPSNKQVPDVTGKTVAEAREAIEKVNLKVGEEIEENSDE
VASGMIIRTDPVAGTQRKEGSTVNLVVSKGAKTLIMEDYTGQTTAQAVERLTDVLKVPKNNIKVEEVETNDAEEGTIFEQ
TPAAGATYDLTSNTKIVLKVAKAVSTIEMPNFGSLQYTYANARNYLISLGIPSSNIERVVDRSVVSSQSDLVTSQSPATG
PVNPKKVKVTLYVTEATTPSSSSSSSSNSSSSSKNTSSSSSSEDETSASSSTHGD

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=197406 WH25_RS03870 WP_046165167.1 811702..813549(+) (stkP) [Streptococcus gordonii strain IE35]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCAAACAAATTGGCCGAGGCGGGATGGCAGATGTCTA
TCTTGCCAAGGATTTGATTTTAGATGGTGAAGAAGTGGCGGTTAAGGTTCTTAGAACCAATTACCAGACGGATCCTATCG
CTGTTGCACGTTTCCAACGAGAAGCGCGTGCCATGGCGGATTTGGACCATCCACATATCGTTCGTGTCACCGATATTGGT
GAAGAAGACGGCCAGCAATATTTGGCTATGGAATATGTAGCTGGCTTGGATCTCAAACGTTATATCAAGGAACACTCTCC
TTTGTCGAACGAAGAGGCCGTTCGAATTATGGGGCAAATTCTTTTAGCCATGCGTTTGGCACATGCTCGTGGGATTGTTC
ACCGAGATTTGAAACCGCAAAACGTTCTCCTGACTCCAGATGGAAATGCTAAGGTAACGGACTTTGGGATTGCGGTTGCC
TTTGCAGAAACAAGTTTGACCCAAACAAATTCCATGCTTGGTAGTGTCCATTATTTGTCTCCTGAGCAGGCGCGTGGTTC
GAAAGCAACTTTCCAAAGCGATATTTATGCGATGGGGATCATCTTTTATGAGATGCTGACTGGTCATATTCCTTATGATG
GGGATAGTGCAGTGACGATCGCTCTACAACATTTCCAAAAACCATTGCCGTCCATTATTGCTGAAAACGCCAATGTTCCG
CAGTCTTTGGAAAATGTTATTATTAAGGCTACTGCTAAAAAGCTGACAGATCGATATCAGAGTGTTTCGGATATGTATGT
AGATCTGTCTAGCTGCCTGTCACCTGAACGACGGAATGAAAAGAAACTGATGTTTGATGACGCGGTAAAAGCGGATACTA
AAACACTTCCGAAGATTCCACAAGTCACACCTCCTGTAGCTTCTAGAGTAAATAATGATCCAGCTACAGATGTTGAACAG
AAAGTCCCTCAAGTTGCACCGCCAACAAAACCTAAGAAAAAGCATCATTTGAGAGCGAGATACAAGGTTTTGTTAGCTGC
AGTATTTCTGGTCATTGCTGCTTTTCTAGCTTTGCTCTATCTAACACCATCTAATAAGCAGGTTCCAGATGTTACTGGCA
AGACCGTTGCTGAAGCTAGAGAAGCGATTGAAAAAGTCAATTTAAAAGTTGGCGAAGAAATAGAAGAGAATAGTGATGAA
GTAGCTTCTGGAATGATTATTCGAACAGATCCAGTGGCAGGGACTCAGAGAAAAGAAGGCAGCACGGTTAATTTAGTTGT
TTCTAAGGGAGCTAAAACGCTGATCATGGAAGACTATACTGGTCAAACTACTGCCCAAGCTGTTGAAAGGCTCACGGATG
TTCTAAAAGTTCCAAAAAACAATATTAAAGTTGAAGAAGTTGAAACAAACGATGCAGAAGAAGGGACAATTTTTGAACAG
ACACCAGCTGCGGGAGCTACCTATGATCTCACTTCAAATACGAAGATTGTCTTAAAGGTAGCCAAAGCAGTATCAACGAT
TGAAATGCCAAACTTTGGTAGCCTTCAATATACTTATGCAAACGCTCGGAATTATCTGATTTCTCTAGGAATTCCATCTA
GTAACATTGAAAGAGTCGTGGATCGTTCGGTTGTGTCGAGTCAATCTGATTTGGTGACATCACAATCTCCAGCAACTGGA
CCAGTTAATCCTAAGAAGGTAAAAGTGACCTTGTATGTCACTGAAGCAACTACTCCAAGTTCAAGTTCTAGCTCGAGCTC
GAATTCTTCTTCTAGCAGTAAGAATACGTCATCGTCAAGTTCTTCAGAAGATGAAACTTCAGCGTCAAGTTCTACACATG
GTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(435-502)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(508-574)

Protein kinase domain (Pkinase)

(12-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

70.543

83.902

0.592
  stkP Streptococcus pneumoniae D39

70.349

83.902

0.59
  stkP Streptococcus pneumoniae R6

70.349

83.902

0.59
  stkP Streptococcus pneumoniae Rx1

70.155

83.902

0.589
  pknB Streptococcus mutans UA159

57.168

93.008

0.532
  stkP/pknB Streptococcus salivarius strain HSISS4

57.847

89.106

0.515

Multiple sequence alignment