Detailed information NTG0197073

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: BB313_RS01340
• Genome accession: NZ_CP021865
• Coordinates: 216701..217162 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SG-M50
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 211701..222162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BB313_RS01305 (BB313_01300)	-	213316..213681 (+)	366	WP_000285373.1	DUF1033 family protein	-
BB313_RS01315 (BB313_01310)	comGA	213854..214825 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
BB313_RS01320 (BB313_01315)	comGB	214719..215762 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
BB313_RS01325 (BB313_01320)	comGC/cglC	215759..216088 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
BB313_RS01330 (BB313_01325)	comGD	216063..216476 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
BB313_RS01335 (BB313_01330)	comGE	216448..216747 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
BB313_RS01340 (BB313_01335)	comGF	216701..217162 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
BB313_RS01345 (BB313_01340)	comGG	217140..217511 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
BB313_RS01350 (BB313_01345)	comGH	217626..218600 (+)	975	WP_001008574.1	class I SAM-dependent methyltransferase	Machinery gene
BB313_RS01355 (BB313_01350)	-	218632..219825 (+)	1194	WP_000047534.1	acetate kinase	-
BB313_RS01360 (BB313_01355)	-	219977..220183 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
BB313_RS01365 (BB313_01360)	-	220242..220379 (+)	138	WP_001865900.1	hypothetical protein	-
BB313_RS01370 (BB313_01365)	-	220420..220875 (+)	456	WP_000905673.1	hypothetical protein	-
BB313_RS01375 (BB313_01370)	-	220944..221609 (+)	666	WP_000008113.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=197073 BB313_RS01340 WP_001874812.1 216701..217162(+) (comGF) [Streptococcus agalactiae strain SG-M50]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=197073 BB313_RS01340 WP_001874812.1 216701..217162(+) (comGF) [Streptococcus agalactiae strain SG-M50]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373