Detailed information NTG0196571

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: BHS01_RS03935
• Genome accession: NZ_CP017195
• Coordinates: 793652..794515 (+)
• Length: 287 a.a.
• NCBI ID: WP_109834812.1
• Uniprot ID: A0A7L4WBZ8
• Organism: Lactococcus paracarnosus strain TMW 2.1615
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 788652..799515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BHS01_RS03910 (BHS01_03905)	-	789909..790244 (+)	336	WP_109834817.1	hypothetical protein	-
BHS01_RS03915 (BHS01_03910)	-	790241..790684 (+)	444	WP_109834816.1	hypothetical protein	-
BHS01_RS03920 (BHS01_03915)	-	791259..792548 (+)	1290	WP_109834815.1	pyrimidine-nucleoside phosphorylase	-
BHS01_RS03925 (BHS01_03920)	deoC	792545..793210 (+)	666	WP_109834814.1	deoxyribose-phosphate aldolase	-
BHS01_RS03930 (BHS01_03925)	-	793194..793586 (+)	393	WP_162542433.1	cytidine deaminase	-
BHS01_RS03935 (BHS01_03930)	dprA	793652..794515 (+)	864	WP_109834812.1	DNA-processing protein DprA	Machinery gene
BHS01_RS03940 (BHS01_03935)	purD	794756..796009 (+)	1254	WP_109834811.1	phosphoribosylamine--glycine ligase	-
BHS01_RS03945 (BHS01_03940)	purE	796002..796496 (+)	495	WP_109834810.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
BHS01_RS03950 (BHS01_03945)	purK	796510..797559 (+)	1050	WP_109835556.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
BHS01_RS03955 (BHS01_03950)	purB	797707..798999 (+)	1293	WP_109834809.1	adenylosuccinate lyase	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 32363.32 Da
• Isoelectric Point: 9.4485

>NTDB_id=196571 BHS01_RS03935 WP_109834812.1 793652..794515(+) (dprA) [Lactococcus paracarnosus strain TMW 2.1615]
MTNFDLYRLKKAGMSNLVLNQFLAFISSVRSDSRQHDMMTQLPKFIRQATMKHKGLFWERFKQLDTKALRQEFLKFSSFS
ILDKFYPEYLREIHNPPVLLFYQGDIGLLAMEKIAFVGSRSCSKQGIASIQKIIKELNNQFVVISGLARGIDTACHLATI
KNGGRTISVIGTGLDVSYPRENEQLQSFIAKNHLIITEYGPGEQPLKYHFPERNRIIAGLSRGVVVTEAKRRSGSLITCE
RAMESGRDVFAIPGTISDGLSDGCHHLIQEGAKLVYQGQDILSEYPD

Nucleotide

• Length: 864 bp

>NTDB_id=196571 BHS01_RS03935 WP_109834812.1 793652..794515(+) (dprA) [Lactococcus paracarnosus strain TMW 2.1615]
ATGACTAATTTTGATTTGTATCGCTTAAAGAAAGCAGGAATGAGTAATTTAGTACTAAATCAGTTTTTAGCGTTCATCAG
CAGTGTAAGATCAGATAGTAGGCAACATGATATGATGACACAGTTGCCAAAATTTATCCGACAGGCTACTATGAAGCATA
AGGGGTTATTTTGGGAAAGGTTCAAGCAGTTAGATACAAAAGCCTTACGACAAGAATTTTTAAAGTTCTCATCATTCTCT
ATCTTAGACAAGTTCTATCCCGAGTATCTGCGGGAAATACATAATCCACCAGTATTACTCTTTTATCAAGGAGATATTGG
GTTACTGGCCATGGAAAAAATAGCCTTTGTTGGCAGTAGATCCTGCAGCAAACAAGGCATTGCTAGTATTCAAAAAATCA
TTAAAGAGTTAAACAATCAGTTTGTTGTGATCAGCGGATTGGCACGGGGAATTGATACTGCTTGTCATCTTGCTACCATC
AAAAATGGCGGTAGGACGATTTCAGTGATTGGGACGGGTTTGGATGTCTCTTATCCCAGGGAAAACGAGCAACTACAGTC
ATTCATCGCAAAAAATCATCTGATTATAACAGAGTATGGACCAGGTGAGCAACCATTGAAATATCATTTTCCAGAAAGGA
ATAGGATCATAGCAGGTCTCTCTAGGGGTGTGGTCGTGACAGAGGCCAAGCGTCGGTCAGGCAGTTTGATTACCTGTGAG
AGGGCCATGGAGTCAGGACGCGATGTCTTTGCCATACCTGGAACTATCTCGGACGGCTTGTCAGATGGGTGTCATCATTT
GATTCAAGAAGGTGCTAAGTTGGTCTATCAAGGCCAAGATATTTTGTCTGAATATCCTGATTGA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-69)

• DNA recombination-mediator protein A (DNA_processg_A) (79-276)

3D structure

• AlphaFold DB: A0A7L4WBZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	61.754	99.303	0.613
dprA	Streptococcus mutans UA159	60	99.303	0.596
dprA/cilB/dalA	Streptococcus mitis SK321	58.246	99.303	0.578
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.246	99.303	0.578
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.895	99.303	0.575
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.895	99.303	0.575
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.895	99.303	0.575
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.895	99.303	0.575