Detailed information NTG0195765

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: CDH85_RS01620
• Genome accession: NZ_CP021769
• Coordinates: 282778..283239 (-)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain B509
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 277778..288239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CDH85_RS01585 (CDH85_01575)	-	278331..278996 (-)	666	WP_000008113.1	type II CAAX endopeptidase family protein	-
CDH85_RS01590 (CDH85_01580)	-	279065..279520 (-)	456	WP_000905673.1	hypothetical protein	-
CDH85_RS10855 (CDH85_01585)	-	279561..279698 (-)	138	WP_001865900.1	hypothetical protein	-
CDH85_RS01600 (CDH85_01590)	-	279757..279963 (-)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
CDH85_RS01605 (CDH85_01595)	-	280115..281308 (-)	1194	WP_000047534.1	acetate kinase	-
CDH85_RS01610 (CDH85_01600)	comGH	281340..282314 (-)	975	WP_001008574.1	N-6 DNA methylase	Machinery gene
CDH85_RS01615 (CDH85_01605)	comGG	282429..282800 (-)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
CDH85_RS01620 (CDH85_01610)	comGF	282778..283239 (-)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
CDH85_RS01625 (CDH85_01615)	comGE	283193..283492 (-)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
CDH85_RS01630 (CDH85_01620)	comGD	283464..283877 (-)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
CDH85_RS01635 (CDH85_01625)	comGC/cglC	283852..284181 (-)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
CDH85_RS01640 (CDH85_01630)	comGB	284178..285221 (-)	1044	WP_275426763.1	competence type IV pilus assembly protein ComGB	Machinery gene
CDH85_RS01645 (CDH85_01635)	comGA	285115..286086 (-)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
CDH85_RS01655 (CDH85_01645)	-	286259..286624 (-)	366	WP_000285373.1	DUF1033 family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=195765 CDH85_RS01620 WP_001874812.1 282778..283239(-) (comGF) [Streptococcus agalactiae strain B509]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=195765 CDH85_RS01620 WP_001874812.1 282778..283239(-) (comGF) [Streptococcus agalactiae strain B509]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373