Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CDC27_RS17605 Genome accession   NZ_CP021726
Coordinates   3448783..3449907 (-) Length   374 a.a.
NCBI ID   WP_072686347.1    Uniprot ID   -
Organism   Escherichia coli strain Combat11I9     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3443783..3454907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDC27_RS17575 (CDC27_17550) yrdA 3445583..3446137 (+) 555 WP_033814717.1 gamma carbonic anhydrase family protein -
  CDC27_RS17580 (CDC27_17555) yrdB 3446113..3446370 (-) 258 WP_001070590.1 DUF1488 domain-containing protein -
  CDC27_RS17585 (CDC27_17560) aroE 3446367..3447185 (-) 819 WP_033814716.1 shikimate dehydrogenase -
  CDC27_RS17590 (CDC27_17565) tsaC 3447190..3447762 (-) 573 WP_033814715.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  CDC27_RS17595 (CDC27_17570) yrdD 3447767..3448309 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  CDC27_RS17600 (CDC27_17575) smg 3448338..3448811 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  CDC27_RS17605 (CDC27_17580) dprA 3448783..3449907 (-) 1125 WP_072686347.1 DNA-protecting protein DprA Machinery gene
  CDC27_RS17610 (CDC27_17585) def 3450037..3450546 (+) 510 WP_000114984.1 peptide deformylase -
  CDC27_RS17615 (CDC27_17590) fmt 3450561..3451508 (+) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  CDC27_RS17620 (CDC27_17595) rsmB 3451554..3452843 (+) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CDC27_RS17625 (CDC27_17600) trkA 3452865..3454241 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  CDC27_RS17630 (CDC27_17605) mscL 3454371..3454781 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41022.01 Da        Isoelectric Point: 6.3845

>NTDB_id=195490 CDC27_RS17605 WP_072686347.1 3448783..3449907(-) (dprA) [Escherichia coli strain Combat11I9]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGALLVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=195490 CDC27_RS17605 WP_072686347.1 3448783..3449907(-) (dprA) [Escherichia coli strain Combat11I9]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCCTGCCAGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGCTTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388

Multiple sequence alignment