Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   A7J08_RS06065 Genome accession   NZ_CP017088
Coordinates   1212101..1214338 (-) Length   745 a.a.
NCBI ID   WP_148115778.1    Uniprot ID   A0A3Q8BF68
Organism   Streptococcus suis strain SRD478     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1207101..1219338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS06040 (A7J08_05875) tmk 1207206..1207844 (-) 639 WP_024412257.1 dTMP kinase -
  A7J08_RS06045 (A7J08_05880) - 1208019..1208885 (+) 867 WP_002935357.1 YitT family protein -
  A7J08_RS06050 (A7J08_05885) - 1208922..1210193 (-) 1272 WP_024415041.1 toxic anion resistance protein -
  A7J08_RS06055 (A7J08_05890) - 1210199..1211026 (-) 828 WP_053867324.1 hypothetical protein -
  A7J08_RS06060 (A7J08_05895) - 1211120..1211776 (-) 657 WP_053867325.1 CBS domain-containing protein -
  A7J08_RS10420 (A7J08_05900) - 1211959..1212084 (-) 126 Protein_1125 IS982 family transposase -
  A7J08_RS06065 (A7J08_05905) comEC/celB 1212101..1214338 (-) 2238 WP_148115778.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A7J08_RS06070 (A7J08_05910) - 1214322..1214981 (-) 660 WP_148115779.1 helix-hairpin-helix domain-containing protein -
  A7J08_RS06075 (A7J08_05915) - 1215049..1215795 (-) 747 WP_053866958.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  A7J08_RS06080 (A7J08_05920) - 1215943..1217388 (+) 1446 WP_024382741.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  A7J08_RS06085 (A7J08_05925) - 1217541..1218326 (+) 786 WP_044758826.1 ABC transporter ATP-binding protein -
  A7J08_RS06090 (A7J08_05930) - 1218339..1219268 (+) 930 WP_053866959.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83922.81 Da        Isoelectric Point: 8.2302

>NTDB_id=195407 A7J08_RS06065 WP_148115778.1 1212101..1214338(-) (comEC/celB) [Streptococcus suis strain SRD478]
MLRLSKLPCKPIHLAVLAVAAYFAVHSFSLLTIGLLNLVLAVFGFRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLASQEEQVYFQKLTDLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNIFDWLSSWRRQALVHVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNMGFRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSGLVLLLLLVGLFLLYDFHRRKKWVLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSVFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSSGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIGARIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=195407 A7J08_RS06065 WP_148115778.1 1212101..1214338(-) (comEC/celB) [Streptococcus suis strain SRD478]
ATGTTACGGTTGAGTAAGCTCCCTTGTAAACCCATTCACCTGGCAGTCTTGGCGGTGGCAGCATACTTTGCAGTCCACTC
GTTTTCCCTCTTGACAATAGGCCTGCTGAATTTGGTGTTAGCTGTCTTTGGGTTTCGGCAAGGTAAGACGGTTTTCCTCA
AAACGCTGCCGCTTTTAGCCCTGTGCGGTCTGTTTTTCGGCTACCAAAAGGTACAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATTAATGGCGACAGCTTGTCTTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAGCCAGTCAGGAGGAGCAGGTTTATTTTCAAAAGTTGACAGATTTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATCTATCGGACTGTCAAACTGACAGCGATTAAGAAGATTGTTCCTGTCCAGTCTTGGAATATTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAAGCCTTGGTCCATGTCAAAACCAATTTTCCGGCACCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGCGACCTCTATTCTAGTCTGGGCATCATTCATCTCTTC
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAAC
CGTAGATAAGTTGCAGATTCCCTTTTCCATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTTGTGCGGTCCTTGG
TCCAGAAAATTCTGGGCAATATGGGCTTTCGGAAGTTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATTTTG
CCCCGATTTTTACTGACAGCAGGCGGTGTCTTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTTTGTCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCAGTT
ATTTTTCTCTTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCAGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGGGTTGGTCCTCTTGCTTTTGCTAGTCGGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGGTGCTCGGACTGAGCCTGGTTCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAGAACGAGGTGACGGTGGTGGACATTGGGCAGGGGGACAGTGTCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTTTGATTGATGTGGGCGGTCGGGTCGATTTTGCAGCCAAGGAAGCCTGGCAGGAGCGGTCTTCACAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAGATTGGTCGGATTGTCGTGTCGTCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGCTCTTCCTATCCTGAATTTTTAGACCATATCGGAGCCAGGATTGCCC
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCGCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGCACCGATCAGCAAGGAGCAATCCGCTTCCGAGGCTGGAAGGAGTGGAAGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(27-175)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q8BF68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.662

100

0.541
  comEC/celB Streptococcus mitis NCTC 12261

53.197

98.658

0.525
  comEC/celB Streptococcus pneumoniae TIGR4

52.31

98.792

0.517
  comEC/celB Streptococcus pneumoniae Rx1

52.038

98.792

0.514
  comEC/celB Streptococcus pneumoniae D39

52.038

98.792

0.514
  comEC/celB Streptococcus pneumoniae R6

52.038

98.792

0.514
  comEC Lactococcus lactis subsp. cremoris KW2

48.202

100

0.486

Multiple sequence alignment