Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   A7J08_RS02395 Genome accession   NZ_CP017088
Coordinates   462634..464628 (+) Length   664 a.a.
NCBI ID   WP_053866719.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 457634..469628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS02380 (A7J08_02290) fmt 459621..460559 (+) 939 WP_053866721.1 methionyl-tRNA formyltransferase -
  A7J08_RS02385 (A7J08_02295) rsmB 460546..461859 (+) 1314 WP_079739208.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A7J08_RS02390 (A7J08_02300) - 461897..462634 (+) 738 WP_053866720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A7J08_RS02395 (A7J08_02305) stkP 462634..464628 (+) 1995 WP_053866719.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A7J08_RS02400 (A7J08_02310) liaF 465085..465744 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  A7J08_RS02405 (A7J08_02315) - 465741..466757 (+) 1017 WP_002937028.1 sensor histidine kinase -
  A7J08_RS02410 (A7J08_02320) - 466729..467370 (+) 642 WP_079394183.1 response regulator transcription factor -
  A7J08_RS02415 (A7J08_02325) - 467420..468820 (+) 1401 WP_053867074.1 Cof-type HAD-IIB family hydrolase -
  A7J08_RS02420 (A7J08_02330) - 468822..469193 (+) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71371.00 Da        Isoelectric Point: 7.0838

>NTDB_id=195389 A7J08_RS02395 WP_053866719.1 462634..464628(+) (stkP) [Streptococcus suis strain SRD478]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KSPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITREYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSAGSSTSTSTSTGSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=195389 A7J08_RS02395 WP_053866719.1 462634..464628(+) (stkP) [Streptococcus suis strain SRD478]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGGTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGGATTATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGACCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCTCAAGCCAATGTTGAAACGAAAGTACCGCATACAAATAGTTCCGCCCAAGTTTCTGCGACAGAT
AAGAGCCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCACGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCGGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCTGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAGCAGGAAGTTCCACAAGTACAAGTACTTCAACAGGTAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(441-501)

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.481

100

0.526
  stkP Streptococcus pneumoniae D39

52.331

100

0.524
  stkP Streptococcus pneumoniae R6

52.331

100

0.524
  stkP Streptococcus pneumoniae Rx1

52.18

100

0.523
  stkP/pknB Streptococcus salivarius strain HSISS4

52.479

88.102

0.462
  pknB Streptococcus mutans UA159

53.846

82.229

0.443

Multiple sequence alignment