Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   BGL52_RS12035 Genome accession   NZ_CP017065
Coordinates   2429640..2431832 (-) Length   730 a.a.
NCBI ID   WP_087912738.1    Uniprot ID   -
Organism   Lacticaseibacillus casei strain LC5     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2424640..2436832
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BGL52_RS15795 - 2425045..2425212 (+) 168 WP_155807535.1 hypothetical protein -
  BGL52_RS12020 (BGL52_11385) - 2425514..2426491 (+) 978 WP_087912735.1 aldo/keto reductase -
  BGL52_RS12025 (BGL52_11390) - 2426780..2428135 (-) 1356 WP_087912736.1 threonine/serine exporter family protein -
  BGL52_RS12030 (BGL52_11395) - 2428249..2429628 (-) 1380 WP_087912737.1 bacteriocin secretion accessory protein -
  BGL52_RS12035 (BGL52_11400) comA 2429640..2431832 (-) 2193 WP_087912738.1 peptide cleavage/export ABC transporter Regulator
  BGL52_RS15910 - 2432146..2432292 (-) 147 WP_191981858.1 hypothetical protein -
  BGL52_RS12040 (BGL52_11405) - 2432460..2433761 (+) 1302 WP_087912739.1 GHKL domain-containing protein -
  BGL52_RS12045 (BGL52_11410) - 2433763..2434569 (+) 807 WP_087912740.1 response regulator transcription factor -
  BGL52_RS12055 (BGL52_11420) - 2436377..2436661 (-) 285 WP_087912742.1 hypothetical protein -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81732.21 Da        Isoelectric Point: 7.3692

>NTDB_id=195030 BGL52_RS12035 WP_087912738.1 2429640..2431832(-) (comA) [Lacticaseibacillus casei strain LC5]
MFKYKFKLGQATYYKRHYTPQVDERDCGVAALNMLLKFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFNLDDVSYPILVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLSKEEFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPLLARQKVIIANIIVAALLITVISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRHLTDRRLIDGAINVDDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPIETGRGKITFNGAQI
NDVALTTLWQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMKDRTIIFVAHRLTIAAKTEQIVVMDHGEIVEQGNHAELLAK
QGYYARLVSE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=195030 BGL52_RS12035 WP_087912738.1 2429640..2431832(-) (comA) [Lacticaseibacillus casei strain LC5]
ATGTTCAAATACAAATTCAAACTAGGCCAAGCAACATACTACAAACGTCATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTGCTGAAGTTTCATGGGTCCGACTATTCGCTCGCCCATTTACGGCAATTAGCGAAGA
CCGATCAGGAAGGAACGACGGCGTTAGGCATTGTTCGGGCTGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTAATTTAGATGATGTTTCATATCCGATCTTGGTACATGTTTTGAAGCGTGGCGAGCTGTTGCATTA
TTATGTCGTGTTTAAGGCAACGAAGGATCATATCTTAATTGGTGATCCTGACCCTTCAGTCGCAATGACCTGGCTTTCAA
AAGAGGAGTTTGCCAAGGAGTGGTCGGGGGTGGCTATCTTTATTGCTCCTGAACCGCAATATCAACCGCGCAAAGAGGAC
AAAGGCAGTTTGTTTGCCTTCGTGCCGTTGCTCGCGCGGCAAAAAGTGATCATTGCCAATATTATTGTGGCGGCTTTGTT
GATCACGGTGATTAGCATTGTTGGGTCGTATTTTCTGCAATCGATCATTGATACCTACATTCCAAGTGCCATGCGGACGA
CGTTAGGGATGATCGCCAGTGGGCTGATTCTCGCTTACATCCTTCAATCTGTTTTGACGTATGGTCAGAACTTTTTGATG
GCGGTGCTGGGCCAGCGGTTGTCGATTGACGTTATTTTGGGTTACGTTCGGCATCTGTATGAATTACCTATGTCTTTTTT
TGCAACACGTCGAACCGGGGAGATTGTGTCGCGGTTTTCGGATGCCAATAAAATTATCGATGCCTTGGCGAATACGATTA
TGACCCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTCTGGGCATTCAAAATACTACATTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGCTCATCGATTATTGAGGATCTGAACGGTATTGAGACCATTAAGTCGCTGACAGGTGAAA
AGGTCAGTTATGAGCGGGTTGACCGTGAATTCGTCACGTATTTAAAAAAGTCATTCAATTACACGAAAGCCGACCAGCTT
CAACAAGCTATCAAAGGGTTGCTGAAGCTCGTCTTGAATGTGGTGGTGTTGTGGATTGGAGCGAGTCTGGTGATGGCTAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCGTTGCTGTCGTACTTCACCAATCCGTTAGAAAGCATCATTAACT
TGCAACCTAAATTGCAAATGGCCAAGGTGGCGAATAATCGGCTGAATGAGGTTTATCTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCCGCCTGATCGATGGTGCCATCAACGTGGATGATGTTTCCTTTAAGTATGGGTTTGGGCA
GGACATTTTAAAGCATGTCCATCTTGAGGTGCCCGCAAATGCCAAATACACGATTGTCGGCATGAGTGGCTCGGGTAAAT
CAACTTTGGCCAAATTATTGGTCGGTTTTTACCCGATCGAAACAGGCAGGGGAAAAATCACCTTTAATGGCGCGCAGATC
AATGATGTGGCGCTCACGACGCTGTGGCAATATATCGAGTATGTGCCGCAAGAGCCGTTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTCGAAGACGCATGTGCCGTTGCGGAAATTGCCA
CGGATATCATGAATTTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGTATTTTATCAGGCGGGCAGAAGCAG
CGCTTGGCGATTGCGCGGGCGTTGTTGTCGCCGGCCAAAGTGCTGATTTTTGATGAGTCGACTAGCAGTTTGGATACCAT
TACGGAGCGGCGGATTGTGGATCGGTTGTTGGCAATGAAGGATCGAACGATTATTTTTGTCGCCCACCGACTCACCATCG
CGGCTAAAACCGAACAGATTGTGGTGATGGATCATGGAGAAATTGTTGAGCAGGGCAATCATGCCGAACTGCTGGCGAAG
CAGGGATATTATGCGCGGTTGGTGAGTGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(16-152)

ABC transporter transmembrane region (ABC_membrane)

(180-448)

ABC transporter (ABC_tran)

(510-662)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.322

97.945

0.571
  comA Streptococcus pneumoniae Rx1

58.322

97.945

0.571
  comA Streptococcus pneumoniae D39

58.322

97.945

0.571
  comA Streptococcus pneumoniae R6

58.322

97.945

0.571
  comA Streptococcus mitis SK321

57.902

97.945

0.567
  comA Streptococcus pneumoniae TIGR4

57.902

97.945

0.567
  comA Streptococcus gordonii str. Challis substr. CH1

56.904

98.219

0.559
  comA/nlmT Streptococcus mutans UA159

54.432

98.904

0.538

Multiple sequence alignment