Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BGL51_RS01030 Genome accession   NZ_CP017064
Coordinates   183783..184532 (+) Length   249 a.a.
NCBI ID   WP_095559217.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST3     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 178783..189532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BGL51_RS10065 - 179359..179529 (+) 171 WP_023909348.1 hypothetical protein -
  BGL51_RS01005 - 179616..179723 (+) 108 WP_002949251.1 LPXTG cell wall anchor domain-containing protein -
  BGL51_RS01010 (BGL51_01040) - 179810..180550 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  BGL51_RS01015 (BGL51_01045) - 180550..182100 (-) 1551 WP_095559216.1 ABC transporter substrate-binding protein/permease -
  BGL51_RS01020 (BGL51_01050) - 182303..183157 (+) 855 WP_023909349.1 undecaprenyl-diphosphate phosphatase -
  BGL51_RS01025 - 183209..183517 (-) 309 WP_306496352.1 DUF3021 family protein -
  BGL51_RS01030 (BGL51_01055) mecA 183783..184532 (+) 750 WP_095559217.1 adaptor protein MecA Regulator
  BGL51_RS01035 (BGL51_01060) - 184536..185693 (+) 1158 WP_014621088.1 glycosyltransferase family 4 protein -
  BGL51_RS01040 (BGL51_01065) sufC 185854..186624 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  BGL51_RS01045 (BGL51_01070) sufD 186661..187923 (+) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  BGL51_RS01050 (BGL51_01075) - 187977..189209 (+) 1233 WP_011680670.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29140.66 Da        Isoelectric Point: 4.0481

>NTDB_id=194951 BGL51_RS01030 WP_095559217.1 183783..184532(+) (mecA) [Streptococcus thermophilus strain ST3]
MEMKQISETTLKIMITMEDLEEHGMELKDLLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=194951 BGL51_RS01030 WP_095559217.1 183783..184532(+) (mecA) [Streptococcus thermophilus strain ST3]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATCTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

99.598

100

0.996
  mecA Streptococcus thermophilus LMG 18311

98.795

100

0.988
  mecA Streptococcus mutans UA159

57.377

97.992

0.562
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462

Multiple sequence alignment