Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   BFM96_RS05035 Genome accession   NZ_CP016953
Coordinates   1058884..1060758 (+) Length   624 a.a.
NCBI ID   WP_068991143.1    Uniprot ID   A0A917A5E1
Organism   Streptococcus himalayensis strain HTS2     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1053884..1065758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS05020 fmt 1055893..1056828 (+) 936 WP_068991134.1 methionyl-tRNA formyltransferase -
  BFM96_RS05025 rsmB 1056818..1058128 (+) 1311 WP_068991137.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BFM96_RS05030 - 1058147..1058887 (+) 741 WP_068991140.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BFM96_RS05035 stkP 1058884..1060758 (+) 1875 WP_068991143.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BFM96_RS05040 liaF 1061189..1061887 (+) 699 WP_068991146.1 cell wall-active antibiotics response protein LiaF -
  BFM96_RS05045 - 1061884..1062900 (+) 1017 WP_068991149.1 sensor histidine kinase -
  BFM96_RS05050 - 1062881..1063513 (+) 633 WP_068991152.1 response regulator transcription factor -
  BFM96_RS05055 - 1063590..1064993 (+) 1404 WP_068991155.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BFM96_RS05060 - 1064990..1065349 (+) 360 WP_068991158.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 69005.20 Da        Isoelectric Point: 7.0462

>NTDB_id=194032 BFM96_RS05035 WP_068991143.1 1058884..1060758(+) (stkP) [Streptococcus himalayensis strain HTS2]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGQEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVEGLDLKRYIKDRGYLTNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPRVP
QALENVVIKATAKKLPDRYQSVAEMYVDLSSSLSYERRTEARLLFDDAGKADTKTLPKMPQPPLQEASARVAQTEPTTPN
KAPISPNLSSKPKKKRRLRTRYKVLMLAVFLVLAALGALIWLSPSSTTVPEVNGQTVAQARSAIEEAGLKVGKEKTEKHD
DIAAGTVIRTEPKAGTQRREGTSVDLVISEGPDTFSIANYIGWKKTDVINDLVQNHKISQEVIRIEEVETNDYEAGTVIE
QTPEARTIYNRADKQRITLRVAKEMANTSMPSYLGSSYEFAVQNLTQILGVKEANIERRTTANPDDNPYGYAAGLIVKQT
PDVNANFSLKSARIVLYIYEPKEDPSTAHSESSSRSSSERRSNSSTEESSDTQPSSTVSSSTIE

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=194032 BFM96_RS05035 WP_068991143.1 1058884..1060758(+) (stkP) [Streptococcus himalayensis strain HTS2]
ATGATTCAAGTCGGCAAAATTTTTGCTGGACGGTATCGAATCATCAAGCAAATAGGCCGTGGGGGGATGGCAGATGTCTA
TCTCGCTAAGGATCTTATTTTAGATGGACAAGAGGTTGCGGTAAAGGTTCTTAGGACCAATTACCAGACCGATCCGATTG
CAGTGGCACGCTTTCAACGTGAAGCCCGTGCCATGGCAGATTTGGATCACCCGCATATCGTTCGGATAACGGACATTGGA
GAAGAAGACGGTCAACAGTATCTTGCAATGGAATATGTGGAAGGACTGGATTTAAAACGTTATATTAAAGACCGAGGCTA
TCTAACTAATGAAGAAGCAGTTCGGATTATGGGGCAAATTCTCTTAGCTATGCGTTTGGCACATACGAGAGGTATTGTTC
ACAGAGATTTGAAACCGCAAAATGTCTTGTTGACACCTGATGGCAATGCCAAGGTGACCGACTTTGGGATTGCAGTGGCA
TTTGCAGAAACCAGTTTGACGCAGACCAATTCGATGCTGGGGTCTGTCCATTACTTGTCTCCAGAGCAAGCACGTGGCTC
CAAAGCAACGGTTCAAAGCGATATCTATGCGATGGGAATTATTTTCTACGAGATGTTAACCGGTCATATTCCTTATGATG
GGGATAGTGCTGTTACCATTGCTCTTCAGCATTTTCAAAAACCGCTCCCTTCCATCATCAGCGAAAATCCTCGTGTACCA
CAAGCTTTGGAAAATGTCGTGATTAAGGCAACGGCCAAGAAATTACCAGACCGCTACCAGTCGGTAGCAGAGATGTATGT
CGATTTATCGAGTAGCCTTTCTTATGAGCGACGAACGGAAGCTAGACTTCTCTTTGATGATGCCGGAAAAGCAGATACCA
AAACTTTACCAAAAATGCCCCAGCCTCCTTTGCAAGAAGCGTCAGCAAGAGTGGCACAAACAGAACCAACGACACCGAAT
AAGGCTCCGATTTCGCCAAATTTGTCCAGTAAGCCTAAGAAAAAACGTCGCTTACGAACAAGATACAAGGTGTTGATGTT
AGCAGTTTTCTTGGTTTTAGCAGCCTTAGGTGCGTTAATCTGGTTAAGCCCATCCAGTACTACGGTCCCAGAAGTCAATG
GCCAGACTGTTGCCCAGGCTCGCTCAGCCATTGAAGAGGCGGGCTTAAAGGTCGGTAAAGAAAAAACAGAAAAGCATGAT
GACATTGCTGCTGGGACAGTCATTCGAACAGAACCCAAGGCAGGGACCCAACGTCGCGAAGGAACCAGTGTTGATTTAGT
GATTTCAGAGGGGCCAGATACCTTTTCTATAGCCAATTATATCGGTTGGAAAAAGACAGATGTCATCAATGACTTGGTTC
AAAATCACAAGATTTCACAAGAAGTCATTCGAATTGAAGAAGTAGAGACCAATGATTATGAAGCTGGAACGGTCATTGAA
CAAACGCCAGAAGCACGAACGATTTATAATCGAGCAGATAAACAGCGTATTACGCTGCGTGTCGCAAAAGAAATGGCCAA
TACCAGCATGCCAAGTTATCTTGGGTCCAGCTACGAATTTGCTGTGCAAAATTTAACACAAATTCTGGGAGTTAAGGAAG
CAAATATCGAAAGACGAACAACGGCCAATCCAGATGATAATCCTTATGGATATGCGGCAGGTTTGATTGTCAAACAAACG
CCAGACGTTAATGCGAACTTTAGCCTAAAGAGTGCACGAATCGTTCTTTATATTTACGAACCGAAAGAAGATCCTTCTAC
CGCTCATTCAGAATCCAGCAGTCGTTCCTCTAGTGAACGCCGCAGTAACTCAAGTACAGAAGAGAGCAGTGATACGCAAC
CTTCTTCCACGGTATCGTCTAGCACGATTGAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(438-503)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(368-429)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.058

93.269

0.588
  stkP Streptococcus pneumoniae D39

62.715

93.269

0.585
  stkP Streptococcus pneumoniae R6

62.715

93.269

0.585
  stkP Streptococcus pneumoniae Rx1

62.543

93.269

0.583
  pknB Streptococcus mutans UA159

54.017

93.75

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

57.621

86.218

0.497

Multiple sequence alignment