Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BFM96_RS04735 Genome accession   NZ_CP016953
Coordinates   991350..992096 (+) Length   248 a.a.
NCBI ID   WP_068994181.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 986350..997096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS04715 rnpM 986974..987270 (+) 297 WP_068990976.1 RNase P modulator RnpM -
  BFM96_RS04720 - 987263..987562 (+) 300 WP_068990979.1 YlxQ-related RNA-binding protein -
  BFM96_RS11530 - 987579..988269 (+) 691 Protein_889 translation initiation factor IF-2 N-terminal domain-containing protein -
  BFM96_RS04725 infB 988377..990362 (+) 1986 Protein_890 translation initiation factor IF-2 -
  BFM96_RS04730 rbfA 990893..991240 (+) 348 WP_068990984.1 30S ribosome-binding factor RbfA -
  BFM96_RS04735 mecA 991350..992096 (+) 747 WP_068994181.1 adaptor protein MecA Regulator
  BFM96_RS04740 - 992093..993250 (+) 1158 WP_068990986.1 glycosyltransferase family 4 protein -
  BFM96_RS04745 sufC 993340..994110 (+) 771 WP_067086477.1 Fe-S cluster assembly ATPase SufC -
  BFM96_RS04750 sufD 994140..995402 (+) 1263 WP_068990990.1 Fe-S cluster assembly protein SufD -
  BFM96_RS04755 - 995408..996637 (+) 1230 WP_068990995.1 cysteine desulfurase -
  BFM96_RS04760 sufU 996624..997058 (+) 435 WP_068990997.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28887.62 Da        Isoelectric Point: 3.9957

>NTDB_id=194019 BFM96_RS04735 WP_068994181.1 991350..992096(+) (mecA) [Streptococcus himalayensis strain HTS2]
MKMKQISDTTVKITIRLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLESGMLSFRVTPKPDRLDIFVTKSAL
DKNLDFNNLTDLPDMEEMAQMTPDEFIKTLEKTILEKSKEDEEAVTSLEQAEVADEEAEQAVFAEEEESQEKYIYYILEF
PTLQETIQFTKTIDYPVDTSELYKMENRYYLTVLVDVEGQSQLYPAWLLAKMREHGEDTVTTRAVLQEHGHLLLVTDAVP
QLQKVSYT

Nucleotide


Download         Length: 747 bp        

>NTDB_id=194019 BFM96_RS04735 WP_068994181.1 991350..992096(+) (mecA) [Streptococcus himalayensis strain HTS2]
ATGAAGATGAAGCAAATTAGCGATACGACGGTGAAGATCACCATTCGCTTAGAAGATTTGGAAGAACGCGGCATGGAAAT
GGCAGACTTTTTAGTTCCGCAGGAAAAAACAGAAGAGTTTTTCTATACGATTTTAGATGAGCTCGAAATGCCAGAAAGTT
TTTTAGAAAGTGGCATGCTTAGTTTTCGCGTGACTCCCAAGCCAGATCGATTGGATATTTTTGTGACAAAATCCGCCCTG
GATAAAAATCTGGATTTTAATAACCTAACGGATTTGCCTGATATGGAGGAGATGGCTCAAATGACGCCAGATGAATTCAT
CAAGACCTTGGAAAAAACAATTTTAGAAAAAAGTAAGGAAGATGAAGAGGCCGTTACAAGTCTTGAGCAGGCAGAAGTTG
CAGATGAGGAGGCCGAGCAAGCGGTATTTGCTGAAGAAGAGGAATCACAGGAAAAATATATCTATTATATTTTGGAATTC
CCAACTTTGCAAGAGACCATTCAATTCACAAAAACGATTGATTATCCAGTAGATACATCAGAACTTTATAAAATGGAAAA
TCGCTATTACTTGACTGTTTTAGTGGATGTGGAAGGTCAATCTCAGCTGTATCCAGCTTGGTTGTTGGCTAAAATGCGAG
AGCATGGGGAAGATACAGTGACCACACGGGCTGTTTTGCAAGAGCATGGTCATCTTTTGTTGGTGACGGATGCAGTCCCT
CAATTGCAGAAGGTTAGCTACACATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae TIGR4

66.26

99.194

0.657
  mecA Streptococcus pneumoniae D39

65.854

99.194

0.653
  mecA Streptococcus pneumoniae R6

65.854

99.194

0.653
  mecA Streptococcus pneumoniae Rx1

65.854

99.194

0.653
  mecA Streptococcus mutans UA159

50

99.194

0.496
  mecA Streptococcus thermophilus LMD-9

44.882

100

0.46
  mecA Streptococcus thermophilus LMG 18311

44.488

100

0.456

Multiple sequence alignment